Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1965566 | 0.84 | ALDH1A1 (0.52) | KMT2AMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL3102000 | 0.79 | ATM (0.50) | KMT2AALDH1A1LMNAHPGDRAB9A | |
| SCHEMBL2743027 | 0.78 | ATM (0.51) | KMT2AALDH1A1LMNAHPGDRAB9A | |
| SCHEMBL10299029 | 0.73 | ATM (0.51) | KMT2AALDH1A1LMNARAB9AMAPT | |
| SCHEMBL7941760 | 0.71 | MLYCD (0.70) | KMT2AMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL11803278 | 0.69 | MEN1 (0.56) | KMT2AMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL10448453 | 0.67 | CA12 (0.46) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL5625621 | 0.66 | SMN1; SMN2 (0.56) | KMT2AMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL5623365 | 0.65 | MAPT (0.56) | KMT2AMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL9557142 | 0.65 | TSHR (0.60) | KMT2AMEN1ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011072199-A2 | WATER-SOLUBLE DEGRADABLE PHOTO-CROSSLINKER | SURMODICS, INC. (US) | 2011-06-16 | — | — | WO | disclosed |
| US-20110144373-A1 | WATER-SOLUBLE DEGRADABLE PHOTO-CROSSLINKER | SURMODICS, INC. (US) | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144373-A1 | WATER-SOLUBLE DEGRADABLE PHOTO-CROSSLINKER | PLG, USP28, DCLRE1A | KMT2A 3247/4885MEN1 3394/4885ALDH1A1 1181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.