SCHEMBL3102000

SCHEMBL3102000

O=C(c1ccccc1)c1ccc(COc2cc(S(=O)(=O)O)cc(S(=O)(=O)O)c2OCc2ccc(C(=O)c3ccccc3)cc2)cc1.[NaH].[NaH]

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.50
PPARG P37231 1/20 0.46
ALDH1A1 P00352 3/20 0.44
HTT P42858 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
SRD5A2 P31213 2/20 0.43
MAPT P10636 2/20 0.43
GAA P10253 1/20 0.43
RAB9A P51151 1/20 0.43
RXRA P19793 7/20 0.40
RXRB P28702 6/20 0.40
RXRG P48443 5/20 0.40
HPGD P15428 1/20 0.40
ADAMTS4 O75173 1/20 0.39
LMNA P02545 1/20 0.39
KMT2A Q03164 1/20 0.39
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2743027 0.99 ATM (0.51) ATMPPARGALDH1A1HTTSMN1; SMN2
SCHEMBL10299029 0.91 ATM (0.51) ATMPPARGALDH1A1HTTSMN1; SMN2
SCHEMBL29785771 0.83 ATM (0.52) ATMPPARGALDH1A1HTTSMN1; SMN2
SCHEMBL117155 0.83 ATM (0.52) ATMPPARGALDH1A1HTTSMN1; SMN2
SCHEMBL1965568 0.79 KMT2A (0.50) ALDH1A1SMN1; SMN2L3MBTL1MAPTRAB9A
SCHEMBL10299026 0.77 ALDH1A1 (0.56) ATMPPARGALDH1A1HTTSMN1; SMN2
SCHEMBL10299023 0.77 ATM (0.53) ATMPPARGALDH1A1HTTSMN1; SMN2
SCHEMBL6659601 0.76 ATM (0.61) ATMALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL9756730 0.75 FOLH1 (0.49) ALDH1A1SMN1; SMN2L3MBTL1MAPTKMT2A
SCHEMBL10448453 0.74 CA12 (0.46) ALDH1A1SMN1; SMN2L3MBTL1MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3039087-B1 CONDUCTIVE POLYMERIC COATINGS, MEDICAL DEVICES, COATING SOLUTIONS AND METHODS HERAEUS MEDICAL COMPONENTS LLC (US) 2023-12-06 EP claimed
US-10800931-B2 Conductive polymeric coatings, medical devices, coating solutions and methods HERAEUS MEDICAL COMPONENTS LLC (US) 2020-10-13 US claimed
US-20170304506-A1 LUBRICIOUS MEDICAL DEVICE COATING WITH LOW PARTICULATES BANK OF MONTREAL, AS COLLATERAL AGENT 2017-10-26 US claimed
US-20160208114-A1 CONDUCTIVE POLYMERIC COATINGS, MEDICAL DEVICES, COATING SOLUTIONS AND METHODS HERAEUS MEDICAL COMPONENTS LLC 2016-07-21 US claimed
US-9375517-B2 Lubricious medical device coating with low particulates SURMODIES, INC. (US) 2016-06-28 US claimed
EP-2804915-B1 LUBRICIOUS MEDICAL DEVICE COATING WITH LOW PARTICULATES SURMODICS INC (US) 2016-03-30 EP claimed
US-20130197433-A1 LUBRICIOUS MEDICAL DEVICE COATING WITH LOW PARTICULATES SURMODICS, INC. (US) 2013-08-01 US claimed
US-20260108663-A1 LOW PARTICULATE LUBRICIOUS COATING WITH VINYL PYRROLIDONE AND ACIDIC POLYMER-CONTAINING LAYERS SURMODICS INC (US) 2026-04-23 US disclosed
US-20260108662-A1 LUBRICIOUS COATING FOR MEDICAL DEVICE SURMODICS INC (US) 2026-04-23 US disclosed
US-20260098225-A1 POLYACRYLIC ACID CONTAINING LUBRICIOUS COATINGS FOR MEDICAL DEVICES WITH ENHANCED PROPERTIES SURMODICS INC (US) 2026-04-09 US disclosed
US-12472288-B2 Lubricious coating for medical device SURMODICS, INC. (US) 2025-11-18 US disclosed
US-12441951-B2 Polyacrylic acid containing lubricious coatings for medical devices with enhanced properties SURMODICS, INC. (US) 2025-10-14 US disclosed
EP-4082598-B1 LOW-FRICTION SEALING DEVICES SURMODICS INC (US) 2025-10-01 EP disclosed
US-20160175489-A1 LOW PARTICULATE LUBRICIOUS COATING WITH VINYL PYRROLIDONE AND ACIDIC POLYMER-CONTAINER LAYERS BANK OF MONTREAL, AS COLLATERAL AGENT 2016-06-23 US disclosed
EP-3012301-A1 LUBRICIOUS MEDICAL DEVICE COATING WITH LOW PARTICULATES SurModics, Inc. (US) 2016-04-27 EP disclosed
EP-2804915-B1 LUBRICIOUS MEDICAL DEVICE COATING WITH LOW PARTICULATES SURMODICS INC (US) 2016-03-30 EP disclosed
US-20150140107-A1 DELIVERY OF HYDROPHOBIC ACTIVE AGENT PARTICLES BANK OF MONTREAL, AS COLLATERAL AGENT 2015-05-21 US disclosed
US-20140193474-A1 LOW PARTICULATE LUBRICIOUS COATING WITH VINYL PYRROLIDONE AND ACIDIC POLYMER-CONTAINING LAYERS BANK OF MONTREAL, AS COLLATERAL AGENT 2014-07-10 US disclosed
US-20130197433-A1 LUBRICIOUS MEDICAL DEVICE COATING WITH LOW PARTICULATES SURMODICS, INC. (US) 2013-08-01 US disclosed
US-20100272774-A1 DEVICES AND METHODS FOR DELIVERY OF BIOACTIVE AGENTS SURMODICS, INC. (US) 2010-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260108662-A1 LUBRICIOUS COATING FOR MEDICAL DEVICE MUC1, ADH1A, PTK2 ATM 117/4885PPARG 3692/4885ALDH1A1 45/4885
US-20260098225-A1 POLYACRYLIC ACID CONTAINING LUBRICIOUS COATINGS FOR MEDICAL DEVICES WITH ENHANCED PROPERTIES CUTA, EED, SELP ATM 1064/4885PPARG 2746/4885ALDH1A1 135/4885
US-20260108663-A1 LOW PARTICULATE LUBRICIOUS COATING WITH VINYL PYRROLIDONE AND ACIDIC POLYMER-CONTAINING LAYERS VCL, RAD54L, SELP ATM 67/4885PPARG 2702/4885ALDH1A1 751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.