Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10854391 | 0.77 | L3MBTL1 (0.41) | HTTL3MBTL1ALDH1A1 | |
| SCHEMBL17427347 | 0.71 | KDM6B (0.31) | — | |
| SCHEMBL8407246 | 0.67 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1 | |
| SCHEMBL11072976 | 0.66 | PDE5A (0.40) | HTTALDH1A1 | |
| SCHEMBL4577350 | 0.66 | — | — | |
| SCHEMBL14498872 | 0.66 | — | — | |
| SCHEMBL22715296 | 0.65 | CSNK2A2 (0.44) | CSNK2A2CSNK2BCSNK2A1HTTL3MBTL1 | |
| SCHEMBL11066997 | 0.64 | MAPT (0.36) | ALDH1A1 | |
| SCHEMBL17727039 | 0.64 | — | — | |
| SCHEMBL757019 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017204316-A1 | 5-OXO-1,2,4-TRIAZINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF | 塩野義製薬株式会社 | 2017-11-30 | — | — | WO | disclosed |