Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | PDE1A | P54750 | 1/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 6/20 | 0.32 |
| ▸ | JAK2 | O60674 | 3/20 | 0.32 |
| ▸ | JAK1 | P23458 | 3/20 | 0.32 |
| ▸ | JAK3 | P52333 | 3/20 | 0.32 |
| ▸ | TYK2 | P29597 | 2/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13219743 | 0.69 | L3MBTL1 (0.49) | RAPGEF4DAOHTTALDH1A1 | |
| SCHEMBL10854391 | 0.67 | L3MBTL1 (0.41) | HTTALDH1A1 | |
| SCHEMBL19655893 | 0.66 | CSNK2A2 (0.33) | HTTALDH1A1 | |
| SCHEMBL11066997 | 0.62 | MAPT (0.36) | ALDH1A1POLB | |
| SCHEMBL13455320 | 0.62 | PDE5A (0.41) | PDE5APDE1APDE1BPDE3BPDE1C | |
| SCHEMBL4020027 | 0.61 | HTR2A (0.33) | HTT | |
| SCHEMBL21306241 | 0.60 | ALDH1A1 (0.41) | PDE5APDE1APDE1BPDE3BPDE1C | |
| SCHEMBL5763194 | 0.60 | PDE5A (0.39) | PDE5APDE1APDE1BPDE3BPDE1C | |
| SCHEMBL7307418 | 0.60 | HRH2 (0.37) | PDE5APDE1APDE1BPDE3BPDE1C | |
| SCHEMBL6958865 | 0.60 | L3MBTL1 (0.37) | SMN1; SMN2ALDH1A1LMNAADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044696-B1 | 5-OXO-2,5,-DIHYDRO-1,2,4-TRIAZINES, METHODS FOR THEIR PRODUCTION, HERBICIDAL COMPOSITIONS COMPRISING THEM, AND THEIR USE AS HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-10-17 | — | — | EP | disclosed |
| US-4451283-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-05-29 | — | — | US | disclosed |
| EP-0044696-A2 | 5-Oxo-2,5,-dihydro-1,2,4-triazines, methods for their production, herbicidal compositions comprising them, and their use as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-01-27 | — | — | EP | disclosed |