SCHEMBL4301050

SCHEMBL4301050

O=S(=O)(O)c1cc(Cl)ccc1-c1ccc(Cl)cc1S(=O)(=O)O.[LiH]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 2/20 0.46
HSP90AA1 P07900 1/20 0.40
MCL1 Q07820 3/20 0.39
ALDH1A1 P00352 3/20 0.39
CES1 P23141 1/20 0.38
NSD2 O96028 1/20 0.38
MMP14 P50281 1/20 0.38
CASP6 P55212 1/20 0.38
TSHR P16473 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
TP53 P04637 1/20 0.38
PPOX P50336 1/20 0.38
GRIK1 P39086 1/20 0.37
GRIK2 Q13002 1/20 0.37
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
TRPV4 Q9HBA0 1/20 0.36
METAP1 P53582 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3699050 1.00 S100A4 (0.46) S100A4HSP90AA1MCL1ALDH1A1CES1
SCHEMBL196568 0.98 S100A4 (0.48) S100A4HSP90AA1MCL1ALDH1A1CES1
SCHEMBL3695968 0.96 S100A4 (0.46) S100A4HSP90AA1MCL1ALDH1A1CES1
SCHEMBL3696775 0.96 S100A4 (0.46) S100A4HSP90AA1MCL1ALDH1A1CES1
SCHEMBL2742906 0.86 S100A4 (0.42) S100A4HSP90AA1MCL1ALDH1A1ALOX15
SCHEMBL6562906 0.83 ACLY (0.47) S100A4HSP90AA1
SCHEMBL3695138 0.83 ALDH1A1 (0.52) MCL1ALDH1A1TSHRL3MBTL1HPGD
Hydrochloric Acid SCHEMBL2766272 0.81 ACLY (0.46) S100A4HSP90AA1
SCHEMBL198460 0.80 MCL1 (0.53) MCL1ALDH1A1TSHRL3MBTL1HPGD
SCHEMBL29384019 0.80 MCL1 (0.53) MCL1ALDH1A1TSHRL3MBTL1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090253015-A1 POLYARYLENE BLOCK COPOLYMER AND USE THEREOF SUMITOMO CHEMICAL COMPANY ,LIMITED (JP) 2009-10-08 US disclosed
EP-1857482-A1 POLYARYLENE BLOCK COPOLYMER AND USE THEREOF Sumitomo Chemical Company, Limited (JP) 2007-11-21 EP disclosed