Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | DDX3X | O00571 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2871480 | 0.72 | HDAC6 (0.56) | HDAC6NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL2873207 | 0.71 | HDAC1 (0.50) | CSNK2A2CSNK2A1HDAC6ALDH1A1MEN1 | |
| SCHEMBL1965022 | 0.70 | BCAT2 (0.44) | ALOX5CSNK2A2CSNK2A1CSNK2BNPC1 | |
| SCHEMBL1965024 | 0.68 | CSNK2A2 (0.73) | CSNK2A2CSNK2A1NPC1RAB9AKDM4E | |
| SCHEMBL2871393 | 0.68 | HDAC4 (0.48) | CSNK2A2CSNK2A1HDAC6NPC1RAB9A | |
| SCHEMBL25337640 | 0.67 | GLS (0.56) | — | |
| SCHEMBL4540176 | 0.66 | HDAC1 (0.47) | HDAC6NPC1RAB9AHDAC1 | |
| SCHEMBL2300347 | 0.66 | S1PR1 (0.53) | NPC1RAB9AKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL1965704 | 0.66 | SMN1; SMN2 (0.60) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL741751 | 0.65 | MEN1 (0.58) | ALOX5HDAC6SMN1; SMN2L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334670-A1 | NEW 2-AMIDOTHIADIAZOLE DERIVATIVES | Almirall S.A. (ES) | 2011-06-22 | — | — | EP | disclosed |