Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 2/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | DDX3X | O00571 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | EIF4E | P06730 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1968944 | 0.88 | BCAT2 (0.43) | BCAT2ALOX5PTGESCSNK1A1TYRO3 | |
| SCHEMBL18584726 | 0.86 | BCAT2 (0.61) | BCAT2ALOX5PTGESCSNK1A1TYRO3 | |
| SCHEMBL1964639 | 0.82 | ALDH1A1 (0.39) | BCAT2CSNK1A1TYRO3DYRK1BTRPV1 | |
| SCHEMBL1966405 | 0.80 | BCAT2 (0.40) | BCAT2ALOX5PTGESCSNK1A1TYRO3 | |
| SCHEMBL1968589 | 0.74 | ALDH1A1 (0.40) | BCAT2CSNK1A1TYRO3DYRK1BTRPV1 | |
| SCHEMBL11611572 | 0.73 | NPC1 (0.56) | NPC1RAB9ADDX3XMEN1KMT2A | |
| SCHEMBL1965703 | 0.70 | ALOX5 (0.37) | ALOX5DRD1NPC1RAB9ADDX3X | |
| SCHEMBL12607529 | 0.70 | BCAT2 (0.46) | BCAT2DRD1NPC1RAB9AMEN1 | |
| SCHEMBL12607519 | 0.70 | BCAT2 (0.46) | BCAT2DRD1NPC1RAB9AMEN1 | |
| SCHEMBL3698037 | 0.70 | BCAT2 (0.46) | BCAT2DRD1ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334670-A1 | NEW 2-AMIDOTHIADIAZOLE DERIVATIVES | Almirall S.A. (ES) | 2011-06-22 | — | — | EP | disclosed |