Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 20/20 | 0.61 |
| ▸ | CACNA1H | O95180 | 20/20 | 0.61 |
| ▸ | CACNA1I | Q9P0X4 | 20/20 | 0.61 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30587615 | 0.87 | CACNA1G (0.59) | CACNA1GCACNA1HCACNA1ICACNA1C | |
| SCHEMBL30587614 | 0.87 | CACNA1G (0.59) | CACNA1GCACNA1HCACNA1ICACNA1C | |
| SCHEMBL18365943 | 0.87 | CACNA1G (0.59) | CACNA1GCACNA1HCACNA1ICACNA1C | |
| SCHEMBL30587612 | 0.83 | CACNA1G (0.55) | CACNA1GCACNA1HCACNA1ICACNA1C | |
| SCHEMBL18366115 | 0.83 | CACNA1G (0.55) | CACNA1GCACNA1HCACNA1ICACNA1C | |
| SCHEMBL19659478 | 0.77 | HDAC1 (0.56) | CACNA1GCACNA1HCACNA1ICACNA1C | |
| SCHEMBL17316676 | 0.74 | L3MBTL1 (0.65) | CACNA1GCACNA1HCACNA1ICACNA1C | |
| SCHEMBL6969733 | 0.74 | CACNA1G (0.46) | CACNA1GCACNA1HCACNA1ICACNA1C | |
| SCHEMBL19659010 | 0.73 | MAOA (0.44) | CACNA1GCACNA1HCACNA1I | |
| SCHEMBL27364070 | 0.73 | KLKB1 (0.55) | CACNA1GCACNA1HCACNA1I |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017004500-A9 | BICYCLIC LACTAMS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2017-11-30 | — | — | WO | disclosed |