Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30755248 | 0.87 | HSD17B10 (0.57) | KLKB1ALDH1A1LMNAMAPTPOLB | |
| SCHEMBL15520388 | 0.87 | HSD17B10 (0.57) | KLKB1ALDH1A1LMNAMAPTPOLB | |
| SCHEMBL1416055 | 0.86 | KLKB1 (0.55) | KLKB1ALDH1A1LMNAMAPTPOLB | |
| SCHEMBL27364061 | 0.86 | ADORA2B (0.47) | KLKB1ALDH1A1HTTLMNAMAPT | |
| SCHEMBL752774 | 0.84 | LMNA (0.61) | KLKB1ALDH1A1HTTLMNAMAPT | |
| SCHEMBL30755417 | 0.83 | GRM2 (0.57) | KLKB1ALDH1A1POLBHSD17B10L3MBTL1 | |
| SCHEMBL2824923 | 0.83 | GRM2 (0.57) | KLKB1ALDH1A1POLBHSD17B10L3MBTL1 | |
| SCHEMBL27364059 | 0.81 | LMNA (0.49) | KLKB1ALDH1A1HTTLMNAMAPT | |
| SCHEMBL27364069 | 0.81 | KLKB1 (0.44) | KLKB1ALDH1A1HTTLMNAMAPT | |
| SCHEMBL19300037 | 0.81 | HSD17B10 (0.51) | KLKB1ALDH1A1HTTLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026483-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |