Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | ESRRB | O95718 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19660210 | 0.86 | KMT2A (0.49) | KMT2AL3MBTL1LOXL2MEN1NPC1 | |
| SCHEMBL6509897 | 0.80 | KMT2A (0.72) | KMT2AL3MBTL1ESRRBMEN1NPC1 | |
| SCHEMBL19660004 | 0.80 | PTPN1 (0.50) | KMT2AL3MBTL1ESRRBMAPTALDH1A1 | |
| SCHEMBL23797038 | 0.80 | KMT2A (0.43) | KMT2AL3MBTL1LOXL2MEN1NPC1 | |
| SCHEMBL23797050 | 0.79 | ALOX15 (0.50) | KMT2AL3MBTL1ALDH1A1LMNARAB9A | |
| SCHEMBL11262738 | 0.78 | KMT2A (0.50) | KMT2AL3MBTL1ESRRBMAPTSMN1; SMN2 | |
| SCHEMBL3111391 | 0.76 | LOXL2 (0.66) | KMT2ALOXL2MEN1NPC1MAPT | |
| SCHEMBL639093 | 0.75 | PIM1 (0.45) | KMT2AL3MBTL1ESRRBMAPTALDH1A1 | |
| SCHEMBL26673391 | 0.74 | SLC6A3 (0.45) | KMT2AL3MBTL1ESRRBMEN1NPC1 | |
| SCHEMBL11576141 | 0.74 | KMT2A (0.50) | KMT2AL3MBTL1MEN1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464248-B1 | 3-OXO-2,6-DIPHENYL-2,3-DIHYDROPYRIDAZINE-4-CARBOXAMIDES | Bayer Pharma AG (DE) | 2021-09-08 | — | — | EP | disclosed |
| WO-2017202816-A1 | 3-OXO-2,6-DIPHENYL-2,3-DIHYDROPYRIDAZINE-4-CARBOXAMIDES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-11-30 | — | — | WO | disclosed |