Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19660210 | 0.81 | KMT2A (0.49) | KMT2AL3MBTL1MEN1NPC1ALDH1A1 | |
| SCHEMBL19660211 | 0.80 | KMT2A (0.47) | KMT2AL3MBTL1MEN1NPC1ALDH1A1 | |
| SCHEMBL19642965 | 0.69 | TSHR (0.46) | KMT2AMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL3111391 | 0.68 | LOXL2 (0.66) | KMT2AMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL11986999 | 0.67 | L3MBTL1 (0.48) | KMT2AL3MBTL1MEN1NPC1ALDH1A1 | |
| SCHEMBL11037686 | 0.66 | MAPT (0.53) | KMT2AL3MBTL1MEN1NPC1ALDH1A1 | |
| SCHEMBL6844835 | 0.64 | LOXL2 (0.59) | KMT2AMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL13831355 | 0.64 | RAB9A (0.39) | KMT2AL3MBTL1MEN1NPC1ALDH1A1 | |
| SCHEMBL10948186 | 0.63 | CA1 (0.66) | KMT2AL3MBTL1MEN1NPC1ALDH1A1 | |
| SCHEMBL19659999 | 0.63 | L3MBTL1 (0.60) | KMT2AL3MBTL1MEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464248-B1 | 3-OXO-2,6-DIPHENYL-2,3-DIHYDROPYRIDAZINE-4-CARBOXAMIDES | Bayer Pharma AG (DE) | 2021-09-08 | — | — | EP | disclosed |