Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MITF | O75030 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1691901 | 0.78 | HTT (0.71) | RAB9ANPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL17503944 | 0.72 | KLKB1 (0.68) | RAB9ASMN1; SMN2MEN1KMT2ADRD2 | |
| SCHEMBL5593623 | 0.72 | DRD2 (0.57) | RAB9AMEN1KMT2ADRD2DRD4 | |
| SCHEMBL118764 | 0.70 | GFER (0.71) | RAB9ASMN1; SMN2POLBDRD2DRD4 | |
| SCHEMBL28842593 | 0.70 | GFER (0.71) | RAB9ASMN1; SMN2POLBDRD2DRD4 | |
| SCHEMBL10642561 | 0.70 | RAB9A (1.00) | RAB9ANPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL17503951 | 0.70 | DRD2 (0.51) | RAB9ASMN1; SMN2MEN1KMT2ADRD2 | |
| SCHEMBL19031533 | 0.70 | DRD2 (0.51) | RAB9ASMN1; SMN2MEN1KMT2ADRD2 | |
| SCHEMBL28685921 | 0.70 | LMNA (0.62) | SMN1; SMN2MEN1KMT2APOLBDRD2 | |
| SCHEMBL18980077 | 0.70 | RAB9A (0.58) | RAB9ANPSR1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017210685-A1 | PYRADAZINONE DERIVATIVES AND THE COMPOSITIONS AND METHODS OF TREATMENT REGARDING THE SAME | An2H Discovery Limited (IE) | 2017-12-07 | — | — | WO | disclosed |