Sugi Predict

Sugi Predict / Compounds / SCHEMBL1967579

SCHEMBL1967579

SCHEMBL1967579

Cc1cccn2c(NC3CCCCC3)c(-c3ccccc3Cl)nc12

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 2/20 0.65
▸ BACE1 P56817 1/20 0.56
▸ ADORA1 P30542 2/20 0.48
▸ TRIM24 O15164 2/20 0.45
▸ TRIM33 Q9UPN9 2/20 0.45
▸ ADORA3 P0DMS8 1/20 0.45
▸ ADORA2A P29274 1/20 0.45
▸ GAA P10253 5/20 0.43
▸ ALDH1A1 P00352 3/20 0.43
▸ KDM4E B2RXH2 2/20 0.43
▸ CYP1A2 P05177 1/20 0.43
▸ CYP3A4 P08684 1/20 0.43
▸ CYP2D6 P10635 1/20 0.43
▸ CYP2C9 P11712 1/20 0.43
▸ CYP2C19 P33261 1/20 0.43
▸ GFER P55789 1/20 0.43
▸ TP53 P04637 1/20 0.43
▸ POLB P06746 1/20 0.43
▸ BRD4 O60885 1/20 0.42
▸ MAPT P10636 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1970170 0.99 ALOX5 (0.63) ALOX5BACE1ADORA1TRIM24TRIM33
SCHEMBL5127843 0.87 ALOX5 (0.65) ALOX5BACE1ADORA1TRIM24TRIM33
SCHEMBL2992223 0.85 ALOX5 (0.63) ALOX5BACE1ADORA1TRIM24TRIM33
SCHEMBL5168420 0.85 ALOX5 (0.66) ALOX5BACE1ADORA1TRIM24TRIM33
SCHEMBL15152567 0.83 ALOX5 (0.47) ALOX5BACE1ADORA1TRIM24TRIM33
SCHEMBL1967241 0.82 SALL4 (0.47) ALOX5BACE1ADORA1TRIM24TRIM33
SCHEMBL1965252 0.81 ADORA1 (0.64) ALOX5BACE1ADORA1TRIM24TRIM33
SCHEMBL1970474 0.80 ALDH1A1 (0.63) ALOX5BACE1ADORA1TRIM24TRIM33
SCHEMBL5165713 0.80 ALOX5 (0.78) ALOX5BACE1ADORA1GAAALDH1A1
SCHEMBL1966519 0.79 ALDH1A1 (0.66) ALOX5BACE1ADORA1TRIM24TRIM33

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023158646-A1 AUTOLOGOUS STEM CELL VACCINE AND METHODS RUSYN ELENA (US) 2023-08-24 — — WO claimed
US-20230256065-A1 AUTOLOGOUS STEM CELL VACCINE AND METHODS RUSYN ELENA (US) 2023-08-17 — — US claimed
CN-216695019-U Acquisition system for multiplexing laser and optical fiber gyroscope 中国船舶重工集团公司第七0七研究所 2022-06-07 — — CN claimed
US-12552882-B2 Polymeric disinfectants and uses thereof TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) 2026-02-17 — — US disclosed
US-20250387582-A1 PATIENT INTERFACE AND COMPONENT PARTS FISHER & PAYKEL HEALTHCARE LTD (NZ) 2025-12-25 — — US disclosed
US-12499971-B2 Systematic screening and mapping of regulatory elements in non-coding genomic regions, methods, compositions, and applications thereof THE BROAD INSTITUTE, INC. (US) 2025-12-16 — — US disclosed
EP-4237493-B1 POLYMERIC DISINFECTANTS AND USES THEREOF TECHNION RES & DEV FOUNDATION (IL) 2025-12-10 — — EP disclosed
US-12410116-B2 Compounds and use thereof in methods of treatment THE UNIVERSITY OF QUEENSLAND (AU) 2025-09-09 — — US disclosed
US-20250223579-A1 NOVEL CRISPR ENZYMES AND SYSTEMS BROAD INST INC (US) 2025-07-10 — — US disclosed
US-20250213568-A1 KIF5B-RET FUSION MOLECULES AND USES THEREOF FOUNDATION MEDICINE, INC. (US) 2025-07-03 — — US disclosed
US-20250191649-A1 3D DRAM with Vertical Bit Lines Katholieke Universiteit Leuven, KU LEUVEN R&D (BE) 2025-06-12 — — US disclosed
US-8501767-B2 Imidazopyridines and imidazopyrimidines as HIV-1 reverse transcriptase inhibitors CSIR (ZA) 2013-08-06 — — US disclosed
US-8501767-B2 Imidazopyridines and imidazopyrimidines as HIV-1 reverse transcriptase inhibitors CSIR (ZA) 2013-08-06 — — US disclosed
US-8501767-B2 Imidazopyridines and imidazopyrimidines as HIV-1 reverse transcriptase inhibitors CSIR (ZA) 2013-08-06 — — US disclosed
US-20110312957-A1 IMIDAZOPYRIDINES AND IMIDAZOPYRIMIDINES AS HIV-I REVERSE TRANSCRIPTASE INHIBITORS CSIR (ZA) 2011-12-22 — — US disclosed
US-20110312957-A1 IMIDAZOPYRIDINES AND IMIDAZOPYRIMIDINES AS HIV-I REVERSE TRANSCRIPTASE INHIBITORS CSIR (ZA) 2011-12-22 — — US disclosed
US-20110312957-A1 IMIDAZOPYRIDINES AND IMIDAZOPYRIMIDINES AS HIV-I REVERSE TRANSCRIPTASE INHIBITORS CSIR (ZA) 2011-12-22 — — US disclosed
EP-2334675-A1 IMIDAZOPYRIDINES AND IMIDAZOPYRIMIDINES AS HIV-I REVERSE TRANSCRIPTASE INHIBITORS CSIR (ZA) 2011-06-22 — — EP disclosed
WO-2010032195-A1 IMIDAZOPYRIDINES AND IMIDAZOPYRIMIDINES AS HIV-I REVERSE TRANSCRIPTASE INHIBITORS CSIR (ZA) 2010-03-25 — — WO disclosed
WO-2010032195-A1 IMIDAZOPYRIDINES AND IMIDAZOPYRIMIDINES AS HIV-I REVERSE TRANSCRIPTASE INHIBITORS CSIR (ZA) 2010-03-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250387582-A1 PATIENT INTERFACE AND COMPONENT PARTS RAE1, EXOSC9, SET ALOX5 2804/4885BACE1 3644/4885ADORA1 2654/4885
US-12552882-B2 Polymeric disinfectants and uses thereof PIK3C3, POLR1C, CUTA ALOX5 754/4885BACE1 3705/4885ADORA1 2722/4885
US-20110312957-A1 IMIDAZOPYRIDINES AND IMIDAZOPYRIMIDINES AS HIV-I REVERSE TRANSCRIPTASE INHIBITORS TYMP, IMPDH1, DPYD ALOX5 3673/4885BACE1 2906/4885ADORA1 1122/4885
US-12410116-B2 Compounds and use thereof in methods of treatment SOX18, PROX1, RUNX1 ALOX5 2213/4885BACE1 4557/4885ADORA1 4841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.