SCHEMBL19678501

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21705618	0.85	KMT2A (0.36)	ELANEKMT2AHTTSMN1; SMN2TDP1
	SCHEMBL21705622	0.83	GABRP (0.38)	KMT2AHTTSMN1; SMN2TDP1GABRP
	SCHEMBL21705623	0.80	SLC6A4 (0.37)	KMT2AHTTSMN1; SMN2TDP1MEN1
	SCHEMBL21711248	0.78	HTT (0.31)	KMT2AHTTSMN1; SMN2TDP1HPGD
	SCHEMBL19678524	0.78	GRM4 (0.38)	KMT2AHTTSMN1; SMN2TDP1L3MBTL1
	SCHEMBL22097556	0.77	ACACB (0.36)	KMT2AHTTSMN1; SMN2TDP1POLB
	SCHEMBL24632264	0.76	GABRP (0.32)	GABRPGABRDGABRA1TSHRGABRB1
	SCHEMBL19846256	0.76	—	—
	SCHEMBL19846331	0.76	HTT (0.32)	KMT2AHTT
	SCHEMBL27541704	0.75	KMT2A (0.59)	ELANEKMT2AHTTSMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.