Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 3/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.42 |
| ▸ | EBP | Q15125 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | GUSB | P08236 | 2/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9801649 | 0.92 | KEAP1 (0.39) | SIGMAR1KCNJ1KCNH2 | |
| SCHEMBL9801938 | 0.90 | KCNJ1 (0.37) | GNAI3GNAO1GNAI1EBPSIGMAR1 | |
| SCHEMBL9801120 | 0.86 | KCNJ1 (0.38) | SIGMAR1KCNJ1KCNH2 | |
| SCHEMBL9801503 | 0.85 | SIGMAR1 (0.42) | SIGMAR1KCNJ1KCNH2 | |
| SCHEMBL9801172 | 0.84 | MAPK1 (0.40) | SIGMAR1KCNJ1KCNH2 | |
| SCHEMBL9801539 | 0.82 | MAPK1 (0.48) | SIGMAR1KCNJ1KCNH2 | |
| SCHEMBL9801487 | 0.80 | ALOX15 (0.43) | GNAI3GNAO1GNAI1SIGMAR1KCNJ1 | |
| SCHEMBL6277287 | 0.78 | GNAI3 (0.63) | GNAI3GNAO1GNAI1 | |
| SCHEMBL28822838 | 0.78 | SIGMAR1 (0.38) | EBPSIGMAR1KCNJ1KCNH2 | |
| SCHEMBL8736521 | 0.77 | ALOX15 (0.48) | SIGMAR1KCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170349543-A1 | CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349543-A1 | CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS | ABHD16A, AARS1, CFTR | GNAI3 1909/4885GNAO1 3064/4885GNAI1 1484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.