Sugi Predict

Sugi Predict / Compounds / SCHEMBL19682604

SCHEMBL19682604

SCHEMBL19682604

CC(c1cccc(F)c1F)[C@H](N)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CES2 O00748 3/20 0.45
▸ CES1 P23141 3/20 0.45
▸ DPP7 Q9UHL4 3/20 0.41
▸ DPP4 P27487 1/20 0.41
▸ BCHE P06276 1/20 0.39
▸ SLC1A1 P43005 3/20 0.38
▸ GAA P10253 1/20 0.36
▸ SLC7A5 Q01650 1/20 0.36
▸ LMNA P02545 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ DPP8 Q6V1X1 2/20 0.35
▸ DPP9 Q86TI2 2/20 0.35
▸ SLC1A3 P43003 1/20 0.34
▸ SLC1A2 P43004 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20889267 1.00 CES2 (0.45) CES2CES1DPP7DPP4BCHE
SCHEMBL20889385 0.85 DPP7 (0.40) CES2CES1DPP7DPP4SLC1A1
SCHEMBL19682597 0.85 DPP7 (0.40) CES2CES1DPP7DPP4SLC1A1
SCHEMBL20889217 0.85 SLC1A1 (0.38) DPP7DPP4SLC1A1SLC7A5LMNA
SCHEMBL19682369 0.85 SLC1A1 (0.38) DPP7DPP4SLC1A1SLC7A5LMNA
SCHEMBL24311424 0.84 CFD (0.46) SLC1A1LMNASLC1A3SLC1A2
SCHEMBL20889384 0.84 DPP4 (0.39) DPP7DPP4SLC1A1GAASLC7A5
SCHEMBL19682586 0.84 DPP4 (0.39) DPP7DPP4SLC1A1GAASLC7A5
SCHEMBL20889259 0.83 DPP7 (0.39) DPP7DPP4SLC1A1GAASLC7A5
SCHEMBL22507743 0.83 DPP7 (0.39) DPP7DPP4SLC1A1GAASLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10889555-B2 Sulfonamide compound or salt thereof TAIHO PHARMACEUTICAL CO., LTD. (JP) 2021-01-12 — — US disclosed
US-20200405697-A1 Antitumor Agent TAIHO PHARMACEUTICAL CO., LTD. (JP) 2020-12-31 — — US disclosed
US-20200399235-A1 Sulfonamide Compound or Salt Thereof TAIHO PHARMACEUTICAL CO., LTD. (JP) 2020-12-24 — — US disclosed
EP-3718545-A1 ANTITUMOR AGENT Taiho Pharmaceutical Co., Ltd. (JP) 2020-10-07 — — EP disclosed
US-20200157066-A1 Sulfonamide Compound or Salt Thereof TAIHO PHARMACEUTICAL CO., LTD. (JP) 2020-05-21 — — US disclosed
EP-3466934-A1 SULFONAMIDE COMPOUND OR SALT THEREOF Taiho Pharmaceutical Co., Ltd. (JP) 2019-04-10 — — EP disclosed
WO-2017209155-A1 SULFONAMIDE COMPOUND OR SALT THEREOF 大鵬薬品工業株式会社 2017-12-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200399235-A1 Sulfonamide Compound or Salt Thereof RNASEH1, SNRPA1, RRM2 CES2 1840/4885CES1 1731/4885DPP7 3961/4885
US-20200157066-A1 Sulfonamide Compound or Salt Thereof RNASEH1, SNRPA1, RRM2 CES2 1840/4885CES1 1731/4885DPP7 3961/4885
US-10889555-B2 Sulfonamide compound or salt thereof RNASEH1, SNRPA1, RRM2 CES2 1840/4885CES1 1731/4885DPP7 3961/4885
US-20200405697-A1 Antitumor Agent HNRNPR, RRM2, RRM2B CES2 3634/4885CES1 2706/4885DPP7 4703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.