Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 15/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 15/20 | 0.49 |
| ▸ | RRM1 | P23921 | 11/20 | 0.49 |
| ▸ | RRM2B | Q7LG56 | 11/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21957680 | 0.92 | CHRM2 (0.43) | CHRM2CHRM1RRM1RRM2BNOTUM | |
| SCHEMBL19682931 | 0.87 | CHRM2 (0.46) | CHRM2CHRM1RRM1RRM2B | |
| SCHEMBL19682780 | 0.86 | CHRM2 (0.41) | CHRM2CHRM1RRM1RRM2B | |
| SCHEMBL19682933 | 0.84 | CHRM2 (0.40) | CHRM2CHRM1RRM1RRM2BNOTUM | |
| SCHEMBL20872788 | 0.82 | CHRM2 (0.51) | CHRM2CHRM1RRM1RRM2B | |
| SCHEMBL19682334 | 0.74 | CHRM2 (0.42) | CHRM2CHRM1RRM1RRM2B | |
| SCHEMBL20872581 | 0.74 | CHRM2 (0.41) | CHRM2CHRM1RRM1RRM2BNOTUM | |
| SCHEMBL20872934 | 0.72 | CHRM2 (0.32) | CHRM2CHRM1RRM1RRM2B | |
| SCHEMBL22492162 | 0.71 | AKR1B1 (0.37) | — | |
| SCHEMBL20872733 | 0.69 | AR (0.36) | CHRM2CHRM1RRM1RRM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240158383-A1 | RIBONUCLEOTIDE REDUCTASE (RNR) INHIBITORS AND USES THEREOF | BOUNDLESS BIO, INC. | 2024-05-16 | — | — | US | disclosed |
| EP-4301735-A1 | RIBONUCLEOTIDE REDUCTASE (RNR) INHIBITORS AND USES THEREOF | Boundless Bio, Inc. (US) | 2024-01-10 | — | — | EP | disclosed |
| WO-2022187200-A1 | RIBONUCLEOTIDE REDUCTASE (RNR) INHIBITORS AND USES THEREOF | BOUNDLESS BIO, INC. (US) | 2022-09-09 | — | — | WO | disclosed |
| US-10889555-B2 | Sulfonamide compound or salt thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2021-01-12 | — | — | US | disclosed |
| US-20200405697-A1 | Antitumor Agent | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2020-12-31 | — | — | US | disclosed |
| US-20200399235-A1 | Sulfonamide Compound or Salt Thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2020-12-24 | — | — | US | disclosed |
| US-20200361883-A1 | Sulfonamide Compounds and Use Thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2020-11-19 | — | — | US | disclosed |
| EP-3718545-A1 | ANTITUMOR AGENT | Taiho Pharmaceutical Co., Ltd. (JP) | 2020-10-07 | — | — | EP | disclosed |
| US-20200157066-A1 | Sulfonamide Compound or Salt Thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2020-05-21 | — | — | US | disclosed |
| EP-3466934-A1 | SULFONAMIDE COMPOUND OR SALT THEREOF | Taiho Pharmaceutical Co., Ltd. (JP) | 2019-04-10 | — | — | EP | disclosed |
| WO-2017209155-A1 | SULFONAMIDE COMPOUND OR SALT THEREOF | 大鵬薬品工業株式会社 | 2017-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200399235-A1 | Sulfonamide Compound or Salt Thereof | RNASEH1, SNRPA1, RRM2 | CHRM2 4302/4885CHRM1 4399/4885RRM1 5/4885 |
| US-20240158383-A1 | RIBONUCLEOTIDE REDUCTASE (RNR) INHIBITORS AND USES THEREOF | RRM2B, RRM2, RNASE1 | CHRM2 4879/4885CHRM1 4884/4885RRM1 5/4885 |
| US-20200157066-A1 | Sulfonamide Compound or Salt Thereof | RNASEH1, SNRPA1, RRM2 | CHRM2 4302/4885CHRM1 4399/4885RRM1 5/4885 |
| US-20200361883-A1 | Sulfonamide Compounds and Use Thereof | STS, SULT2A1, TPST2 | CHRM2 3967/4885CHRM1 4710/4885RRM1 95/4885 |
| US-10889555-B2 | Sulfonamide compound or salt thereof | RNASEH1, SNRPA1, RRM2 | CHRM2 4302/4885CHRM1 4399/4885RRM1 5/4885 |
| US-20200405697-A1 | Antitumor Agent | HNRNPR, RRM2, RRM2B | CHRM2 4208/4885CHRM1 4101/4885RRM1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.