Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 19/20 | 0.59 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4765990 | 0.86 | TGFBR1 (0.51) | TGFBR1MAPK14PDE10A | |
| SCHEMBL6178215 | 0.81 | TGFBR1 (0.59) | TGFBR1MAPK14 | |
| SCHEMBL11992061 | 0.80 | TGFBR1 (0.66) | TGFBR1MAPK14 | |
| SCHEMBL3244123 | 0.78 | TGFBR1 (0.63) | TGFBR1MAPK14 | |
| Gw786460X SCHEMBL29398528 | 0.77 | TGFBR1 (0.60) | TGFBR1MAPK14 | |
| Gw786460X SCHEMBL144632 | 0.77 | TGFBR1 (0.60) | TGFBR1MAPK14 | |
| Gw786460X SCHEMBL26962436 | 0.76 | TGFBR1 (0.59) | TGFBR1MAPK14 | |
| Gw786460X SCHEMBL29889251 | 0.76 | TGFBR1 (0.59) | TGFBR1MAPK14 | |
| SCHEMBL23389927 | 0.75 | TGFBR1 (0.49) | TGFBR1MAPK14 | |
| SCHEMBL29796380 | 0.75 | TGFBR1 (0.49) | TGFBR1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170349884-A1 | Production of Differentiated Enteroendocrine Cells and Insulin Producing Cells | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. | 2017-12-07 | — | — | US | disclosed |