Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 5/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | IDH2 | P48735 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19684414 | 0.90 | ELANE (0.41) | UBE2MDCUN1D1MEN1KMT2AELANE | |
| SCHEMBL19684522 | 0.86 | ELANE (0.48) | MEN1KMT2AELANENPC1SMN1; SMN2 | |
| SCHEMBL19684419 | 0.86 | ELANE (0.48) | MEN1KMT2AELANENPC1SMN1; SMN2 | |
| SCHEMBL19684403 | 0.82 | ELANE (0.47) | MEN1KMT2AELANESMN1; SMN2AURKA | |
| SCHEMBL19688358 | 0.80 | EPHX2 (0.39) | UBE2MDCUN1D1MEN1KMT2AELANE | |
| SCHEMBL19688816 | 0.80 | EPHX2 (0.40) | UBE2MDCUN1D1MEN1KMT2AEPHX2 | |
| SCHEMBL19688336 | 0.79 | EPHX2 (0.40) | UBE2MDCUN1D1MEN1KMT2AELANE | |
| SCHEMBL19684412 | 0.76 | ELANE (0.43) | MEN1KMT2AELANESMN1; SMN2AURKA | |
| SCHEMBL19684716 | 0.72 | MAPT (0.43) | ELANELDHAIDH2AURKA | |
| SCHEMBL19651226 | 0.72 | ELANE (0.52) | MEN1KMT2AELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017207432-A1 | NOVEL COMPOUNDS | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-12-07 | — | — | WO | disclosed |