SCHEMBL19684414 — predicted protein targets

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	ELANE	P08246	3/20	0.41

▸	KLKB1	P03952	2/20	0.40

▸	UBE2M	P61081	2/20	0.39

▸	DCUN1D1	Q96GG9	2/20	0.39

▸	MEN1	O00255	1/20	0.39

▸	KMT2A	Q03164	1/20	0.39

▸	LDHA	P00338	1/20	0.39

▸	KCNJ6	P48051	1/20	0.37

▸	KCNJ5	P48544	1/20	0.37

▸	KCNJ3	P48549	1/20	0.37

▸	EPHX2	P34913	3/20	0.37

▸	AURKA	O14965	1/20	0.36

▸	DRD2	P14416	2/20	0.35

▸	DRD3	P35462	2/20	0.35

▸	RXFP1	Q9HBX9	1/20	0.35

▸	IDH1	O75874	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL19684417	0.90	UBE2M (0.42)	ELANEKLKB1UBE2MDCUN1D1MEN1
SCHEMBL19684522	0.84	ELANE (0.48)	ELANEMEN1KMT2AKCNJ6KCNJ5
SCHEMBL19684419	0.84	ELANE (0.48)	ELANEKLKB1MEN1KMT2ALDHA
SCHEMBL19684403	0.82	ELANE (0.47)	ELANEMEN1KMT2AAURKARXFP1
SCHEMBL19688358	0.80	EPHX2 (0.39)	ELANEKLKB1UBE2MDCUN1D1MEN1
SCHEMBL19688816	0.80	EPHX2 (0.40)	UBE2MDCUN1D1MEN1KMT2ALDHA
SCHEMBL19688336	0.79	EPHX2 (0.40)	ELANEKLKB1UBE2MDCUN1D1MEN1
SCHEMBL19684412	0.76	ELANE (0.43)	ELANEMEN1KMT2AAURKARXFP1
SCHEMBL19651229	0.72	ELANE (0.49)	ELANE
SCHEMBL19684409	0.72	ELANE (0.49)	ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2017207432-A1	NOVEL COMPOUNDS	CHIESI FARMACEUTICI S.P.A. (IT)	2017-12-07	—	—	WO	disclosed