Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | IDH2 | P48735 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19684522 | 0.83 | ELANE (0.48) | MAPTAURKAKDM4ERXFP1ALDH1A1 | |
| SCHEMBL19639784 | 0.78 | RXFP1 (0.48) | MAPTAURKAKDM4ERXFP1ALDH1A1 | |
| SCHEMBL19639813 | 0.78 | AURKA (0.42) | MAPTAURKAKDM4ERXFP1ALDH1A1 | |
| SCHEMBL19684419 | 0.77 | ELANE (0.48) | MAPTAURKAKDM4ERXFP1IDH1 | |
| SCHEMBL19639815 | 0.75 | RORC (0.41) | MAPTAURKAKDM4ERXFP1ALDH1A1 | |
| SCHEMBL19684403 | 0.74 | ELANE (0.47) | MAPTAURKAKDM4ERXFP1ALDH1A1 | |
| SCHEMBL19639785 | 0.73 | ELANE (0.41) | MAPTAURKAKDM4ERXFP1POLB | |
| SCHEMBL19684417 | 0.72 | UBE2M (0.42) | AURKAELANEIDH2LDHA | |
| SCHEMBL19684414 | 0.71 | ELANE (0.41) | AURKARXFP1IDH1ELANELDHA | |
| SCHEMBL19684412 | 0.68 | ELANE (0.43) | MAPTAURKAKDM4ERXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017207432-A1 | NOVEL COMPOUNDS | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-12-07 | — | — | WO | disclosed |