SCHEMBL19686257

SCHEMBL19686257

Cc1coc2ccc(N3c4ccccc4C4(c5ccccc5Oc5ccccc54)c4ccccc43)cc2c1=O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR3E A5X5Y0 1/20 0.33
HTR3B O95264 1/20 0.33
HTR3A P46098 1/20 0.33
HTR3D Q70Z44 1/20 0.33
HTR3C Q8WXA8 1/20 0.33
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.33
CYP17A1 P05093 1/20 0.32
RAB9A P51151 1/20 0.32
POLB P06746 1/20 0.31
KMT2A Q03164 1/20 0.31
MAOB P27338 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
TOP2A P11388 1/20 0.30
USP2 O75604 1/20 0.30
ALOX15 P16050 1/20 0.30
PTPN1 P18031 2/20 0.30
PTPN2 P17706 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19685674 0.92 KDM4E (0.36) ALDH1A1RAB9APOLBKMT2AMAOB
SCHEMBL19686255 0.92 ALDH1A1 (0.37) ALDH1A1TSHRRAB9APOLBKMT2A
SCHEMBL19686256 0.90 KMT2A (0.35) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL19686118 0.90 PTPN1 (0.35) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL19685675 0.88 ALDH1A1 (0.35) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL19685690 0.87 HTR3E (0.32) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL19686111 0.84 USP2 (0.32) USP2ALOX15
SCHEMBL19686058 0.84 USP2 (0.32) ALDH1A1USP2ALOX15
SCHEMBL19685676 0.84 ALDH1A1 (0.33) ALDH1A1TSHRRAB9APOLBKMT2A
SCHEMBL19685682 0.83 KDM4E (0.32) ALDH1A1CYP17A1RAB9AMAOBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-14 US disclosed
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same CYC1, CCNA1, CYCS HTR3E 3625/4885HTR3B 4105/4885HTR3A 3617/4885
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME CYC1, CCNA1, CYCS HTR3E 3625/4885HTR3B 4105/4885HTR3A 3617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.