SCHEMBL19685682

SCHEMBL19685682

Cc1coc2cc(N3c4ccc(F)cc4C4(c5ccccc5Oc5ccccc54)c4cc(F)ccc43)ccc2c1=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.32
HPGD P15428 2/20 0.32
HSD17B10 Q99714 2/20 0.32
USP2 O75604 1/20 0.32
NR3C2 P08235 1/20 0.31
CYP11B1 P15538 2/20 0.31
CYP11B2 P19099 2/20 0.31
CYP17A1 P05093 1/20 0.31
CYP19A1 P11511 1/20 0.31
MAOB P27338 1/20 0.31
PDE10A Q9Y233 1/20 0.30
NPC1 O15118 1/20 0.30
GAA P10253 1/20 0.30
PPARG P37231 1/20 0.30
RAB9A P51151 1/20 0.30
PPARD Q03181 1/20 0.30
PPARA Q07869 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19686118 0.93 PTPN1 (0.35) KDM4EALDH1A1NR3C2MAOBPDE10A
SCHEMBL19685676 0.90 ALDH1A1 (0.33) KDM4EALDH1A1HPGDHSD17B10USP2
SCHEMBL19685674 0.90 KDM4E (0.36) KDM4EALDH1A1HPGDHSD17B10USP2
SCHEMBL19685896 0.85 NR3C2 (0.33) KDM4EALDH1A1NR3C2SMN1; SMN2
SCHEMBL19685854 0.85 PGR (0.32) KDM4EALDH1A1NR3C2SMN1; SMN2
SCHEMBL19685683 0.83 KDM4E (0.38) KDM4EALDH1A1HPGDHSD17B10USP2
SCHEMBL19686255 0.83 ALDH1A1 (0.37) ALDH1A1USP2MAOBPDE10ANPC1
SCHEMBL19686257 0.83 HTR3E (0.33) KDM4EALDH1A1USP2CYP17A1MAOB
SCHEMBL19685917 0.82 ATM (0.34) NR3C2
SCHEMBL19685692 0.82 MAOB (0.37) NR3C2CYP11B1CYP11B2MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-14 US disclosed
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same CYC1, CCNA1, CYCS KDM4E 1138/4885ALDH1A1 572/4885HPGD 901/4885
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME CYC1, CCNA1, CYCS KDM4E 1138/4885ALDH1A1 572/4885HPGD 901/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.