SCHEMBL19686255

SCHEMBL19686255

Cc1ccc2c(c1)C1(c3ccccc3Oc3ccccc31)c1cc(C)ccc1N2c1ccc2occ(C)c(=O)c2c1

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.37
TSHR P16473 3/20 0.37
RAB9A P51151 1/20 0.36
MAOB P27338 3/20 0.35
KMT2A Q03164 3/20 0.35
POLB P06746 1/20 0.35
USP2 O75604 1/20 0.34
CYP3A4 P08684 2/20 0.33
MAPT P10636 2/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
PKM P14618 1/20 0.32
CNR1 P21554 1/20 0.32
GPR55 Q9Y2T6 1/20 0.32
PDE10A Q9Y233 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19685676 0.93 ALDH1A1 (0.33) ALDH1A1TSHRRAB9AMAOBKMT2A
SCHEMBL19686257 0.92 HTR3E (0.33) ALDH1A1TSHRRAB9AMAOBKMT2A
SCHEMBL19686252 0.91 ALDH1A1 (0.37) ALDH1A1TSHRRAB9AMAOBKMT2A
SCHEMBL19686118 0.90 PTPN1 (0.35) ALDH1A1TSHRMAOBPDE10A
SCHEMBL19686109 0.86 PKM (0.32) PKMCNR1GPR55
SCHEMBL19686059 0.86 PKM (0.32) PKMCNR1GPR55
SCHEMBL19685674 0.84 KDM4E (0.36) ALDH1A1RAB9AMAOBKMT2APOLB
SCHEMBL19685682 0.83 KDM4E (0.32) ALDH1A1RAB9AMAOBUSP2NPC1
SCHEMBL19685947 0.82 ALDH1A1 (0.39) ALDH1A1TSHRRAB9AMAOBKMT2A
SCHEMBL19685821 0.82 TP53 (0.34) ALDH1A1RAB9AKMT2AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-14 US disclosed
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same CYC1, CCNA1, CYCS ALDH1A1 572/4885TSHR 3571/4885RAB9A 3747/4885
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME CYC1, CCNA1, CYCS ALDH1A1 572/4885TSHR 3571/4885RAB9A 3747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.