Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.72 |
| ▸ | HTR6 | P50406 | 5/20 | 0.72 |
| ▸ | HTR2A | P28223 | 5/20 | 0.72 |
| ▸ | HTR1D | P28221 | 3/20 | 0.72 |
| ▸ | HTR1B | P28222 | 3/20 | 0.72 |
| ▸ | HTR2C | P28335 | 3/20 | 0.72 |
| ▸ | HTR7 | P34969 | 3/20 | 0.72 |
| ▸ | HTR2B | P41595 | 3/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.72 |
| ▸ | HTR1E | P28566 | 2/20 | 0.72 |
| ▸ | HTR5A | P47898 | 2/20 | 0.72 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.72 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.72 |
| ▸ | HTR3B | O95264 | 1/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.72 |
| ▸ | HTR1F | P30939 | 1/20 | 0.72 |
| ▸ | HTR3A | P46098 | 1/20 | 0.72 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.72 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30418667 | 0.96 | HTR2A (0.70) | HTR1AHTR6HTR2AHTR1DHTR1B | |
| SCHEMBL25241719 | 0.96 | HTR2A (0.70) | HTR1AHTR6HTR2AHTR1DHTR1B | |
| SCHEMBL30630385 | 0.90 | HTR6 (0.72) | HTR1AHTR6HTR2AHTR1DHTR1B | |
| SCHEMBL1970284 | 0.90 | HTR6 (0.72) | HTR1AHTR6HTR2AHTR1DHTR1B | |
| SCHEMBL30419697 | 0.89 | HTR2A (0.67) | HTR1AHTR6HTR2AHTR1DHTR1B | |
| SCHEMBL25282274 | 0.89 | HTR2A (0.67) | HTR1AHTR6HTR2AHTR1DHTR1B | |
| SCHEMBL27084700 | 0.86 | HTR1D (0.74) | HTR1AHTR6HTR2AHTR1DHTR1B | |
| SCHEMBL30630369 | 0.86 | HTR1D (0.74) | HTR1AHTR6HTR2AHTR1DHTR1B | |
| SCHEMBL30630366 | 0.85 | HTR1D (0.54) | HTR1AHTR6HTR2AHTR1DHTR1B | |
| SCHEMBL27084841 | 0.85 | HTR1D (0.54) | HTR1AHTR6HTR2AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250074873-A1 | COMPOUNDS | Psylo Pty Ltd (AU) | 2025-03-06 | — | — | US | disclosed |
| EP-4452938-A1 | COMPOUNDS | Psylo Pty Ltd (AU) | 2024-10-30 | — | — | EP | disclosed |
| CN-118696029-A | Compounds of formula (I) | 普赛洛私人有限公司 | 2024-09-24 | — | — | CN | disclosed |
| US-20240043382-A1 | MODIFIED INDOLE ALKALOIDS FOR THERAPEUTIC USES | COMPASS PATHFINDER LIMITED (GB) | 2024-02-08 | — | — | US | disclosed |
| CN-117120415-A | Modified indole alkaloids for therapeutic use | 指南针探路者有限公司 | 2023-11-24 | — | — | CN | disclosed |
| WO-2023115167-A1 | COMPOUNDS | Psylo Pty Ltd (AU) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023115167-A1 | COMPOUNDS | Psylo Pty Ltd (AU) | 2023-06-29 | — | — | WO | disclosed |
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-09-01 | — | — | US | disclosed |
| EP-2334643-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | Actelion Pharmaceuticals Ltd. (CH) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010044054-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250074873-A1 | COMPOUNDS | NLN, SLC18A2, PYGB | HTR1A 185/4885HTR6 54/4885HTR2A 94/4885 |
| US-20240043382-A1 | MODIFIED INDOLE ALKALOIDS FOR THERAPEUTIC USES | INMT, AANAT, HNMT | HTR1A 181/4885HTR6 57/4885HTR2A 53/4885 |
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | HCRTR2, HCRTR1, HRH3 | HTR1A 56/4885HTR6 177/4885HTR2A 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.