Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.59 |
| ▸ | FAAH | O00519 | 6/20 | 0.57 |
| ▸ | NAAA | Q02083 | 1/20 | 0.56 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26709266 | 1.00 | CASP2 (0.59) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL25730796 | 0.90 | CASP2 (0.62) | CASP2FAAHNAAAMEN1KMT2A | |
| SCHEMBL22857458 | 0.90 | FAAH (0.57) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL20869876 | 0.86 | ACHE (0.52) | CASP2FAAHEPHX2 | |
| SCHEMBL26700973 | 0.86 | CNR1 (0.47) | CASP2FAAHEPHX2MEN1KMT2A | |
| SCHEMBL26700975 | 0.86 | CNR1 (0.47) | CASP2FAAHEPHX2MEN1KMT2A | |
| SCHEMBL22790860 | 0.85 | TLR2 (0.46) | FAAHDNM1EPHX2CNR1CNR2 | |
| SCHEMBL22794195 | 0.85 | TLR2 (0.46) | FAAHDNM1EPHX2CNR1CNR2 | |
| SCHEMBL22692705 | 0.85 | TSHR (0.46) | CASP2FAAHNAAAL3MBTL1MEN1 | |
| SCHEMBL26700966 | 0.84 | ALDH1A1 (0.46) | L3MBTL1KMT2ACNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017139697-A9 | BACTERIA ENGINEERED TO TREAT DISEASES ASSOCIATED WITH HYPERAMMONEMIA | SYNLOGIC, INC. (US) | 2017-12-07 | — | — | WO | disclosed |