Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 7/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NCF1 | P14598 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19687558 | 0.86 | KDM4E (0.40) | KDM4EMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL19631332 | 0.85 | KDM4E (0.41) | KDM4EMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL17784960 | 0.79 | LMNA (0.37) | KDM4EMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28015202 | 0.75 | GRM5 (0.46) | KDM4EMAPTLMNAHTTNPSR1 | |
| SCHEMBL22736821 | 0.74 | PRMT5 (0.35) | KDM4EMAPTLMNAHTTNPSR1 | |
| SCHEMBL21500781 | 0.74 | ALDH1A1 (0.36) | KDM4EMAPTMAPK1LMNAHTT | |
| SCHEMBL21500727 | 0.72 | PRMT5 (0.34) | KDM4EMAPTCYP3A4MAPK1LMNA | |
| SCHEMBL24310536 | 0.71 | PRMT5 (0.33) | KDM4EMAPTLMNAHTTKMT2A | |
| SCHEMBL22084511 | 0.71 | SMN1; SMN2 (0.49) | KDM4EMAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL16741069 | 0.70 | CTSS (0.41) | KDM4EMAPTCYP3A4LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017210335-A1 | IMAGING METHODS USING 18F-RADIOLABELED BIOLOGICS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-12-07 | — | — | WO | disclosed |