Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 9/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYBB | P04839 | 1/20 | 0.36 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19687558 | 0.86 | KDM4E (0.40) | KDM4EMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL19687559 | 0.85 | KDM4E (0.40) | KDM4EMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL19352680 | 0.80 | KDM4E (0.44) | KDM4EMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL17784960 | 0.79 | LMNA (0.37) | KDM4EMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL25100353 | 0.76 | S1PR4 (0.54) | KDM4EMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28015202 | 0.75 | GRM5 (0.46) | KDM4EMAPTLMNAHTTNPSR1 | |
| SCHEMBL15533104 | 0.74 | MAPT (0.69) | KDM4EMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21500781 | 0.74 | ALDH1A1 (0.36) | KDM4EMAPTMAPK1LMNAHTT | |
| SCHEMBL22736821 | 0.74 | PRMT5 (0.35) | KDM4EMAPTLMNAHTTNPSR1 | |
| SCHEMBL19631247 | 0.73 | KDM4E (0.41) | KDM4EMAPTCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11806409-B2 | Imaging methods using 18F-radiolabeled biologics | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-11-07 | — | — | US | disclosed |
| US-20230241258-A1 | IMAGING METHODS USING 18F-RADIOLABELED BIOLOGICS | BRISTOL-MYERS SQUIBB COMPANY | 2023-08-03 | — | — | US | disclosed |
| EP-4218832-A2 | METHODS AND COMPOSITIONS FOR 18F-RADIOLABELING OF THE FIBRONECTIN TYPE (III) DOMAIN | Bristol-Myers Squibb Company (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-3223866-B1 | METHODS AND COMPOSITIONS FOR 18F-RADIOLABELING OF THE FIBRONECTIN TYPE (III) DOMAIN | BRISTOL MYERS SQUIBB CO (US) | 2023-03-08 | — | — | EP | disclosed |
| US-11229713-B2 | Methods and compositions for 18F-radiolabeling of biologics | BRISTOL-MYERS SQUIBB COMPANY (US) | 2022-01-25 | — | — | US | disclosed |
| US-11173219-B2 | PD-L1 binding polypeptides for imaging | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-11-16 | — | — | US | disclosed |
| EP-3827849-A1 | PET-IMAGING IMMUNOMODULATORS | Bristol-Myers Squibb Company (US) | 2021-06-02 | — | — | EP | disclosed |
| EP-3458111-B1 | PET-IMAGING IMMUNOMODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2021-03-03 | — | — | EP | disclosed |
| EP-3702367-A1 | NOVEL PD-L1 BINDING POLYPEPTIDES FOR IMAGING | Bristol-Myers Squibb Company (US) | 2020-09-02 | — | — | EP | disclosed |
| US-20190117801-A1 | PET-IMAGING IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY | 2019-04-25 | — | — | US | disclosed |
| WO-2017210302-A1 | PET IMAGING WITH PD-L1 BINDING POLYPEPTIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-12-07 | — | — | WO | disclosed |
| WO-2017210335-A1 | IMAGING METHODS USING 18F-RADIOLABELED BIOLOGICS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-12-07 | — | — | WO | disclosed |
| WO-2017201111-A1 | PET-IMAGING IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190117801-A1 | PET-IMAGING IMMUNOMODULATORS | CD40, FCGR3B, MIF | KDM4E 4173/4885MAPT 717/4885CYP1A2 3340/4885 |
| US-20230241258-A1 | IMAGING METHODS USING 18F-RADIOLABELED BIOLOGICS | FCGRT, FAP, FUCA1 | KDM4E 4152/4885MAPT 2912/4885CYP1A2 2177/4885 |
| US-11806409-B2 | Imaging methods using 18F-radiolabeled biologics | FCGRT, FAP, FUCA1 | KDM4E 4152/4885MAPT 2912/4885CYP1A2 2177/4885 |
| US-11229713-B2 | Methods and compositions for 18F-radiolabeling of biologics | FCGRT, FGF23, FAP | KDM4E 3633/4885MAPT 3078/4885CYP1A2 1883/4885 |
| US-11173219-B2 | PD-L1 binding polypeptides for imaging | PDCD1LG2, PDCD10, CD274 | KDM4E 4364/4885MAPT 1690/4885CYP1A2 4884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.