Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 3/20 | 0.40 |
| ▸ | PDE4A | P27815 | 3/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19687559 | 0.86 | KDM4E (0.40) | KDM4EMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL19631332 | 0.86 | KDM4E (0.41) | KDM4EMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL25914790 | 0.81 | CHRNB2 (0.43) | KDM4EMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21100993 | 0.81 | CHRNB2 (0.43) | KDM4EMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL17784960 | 0.80 | LMNA (0.37) | KDM4EMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28015202 | 0.80 | GRM5 (0.46) | KDM4EMAPTPDE5ALMNAALDH1A1 | |
| SCHEMBL19342481 | 0.79 | CHRNB2 (0.47) | KDM4EMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL22736821 | 0.78 | PRMT5 (0.35) | KDM4EMAPTPDE5APDE4APDE4B | |
| SCHEMBL21500781 | 0.75 | ALDH1A1 (0.36) | KDM4EMAPTMAPK1LMNAALDH1A1 | |
| SCHEMBL19687565 | 0.74 | LMNA (0.40) | KDM4EMAPTCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017210335-A1 | IMAGING METHODS USING 18F-RADIOLABELED BIOLOGICS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-12-07 | — | — | WO | disclosed |