Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 3/20 | 0.39 |
| ▸ | PDE4A | P27815 | 3/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19631247 | 0.85 | KDM4E (0.41) | LMNAHTTNPSR1TDP1KDM4E | |
| SCHEMBL21100993 | 0.80 | CHRNB2 (0.43) | LMNAHTTNPSR1TDP1KDM4E | |
| SCHEMBL25914790 | 0.80 | CHRNB2 (0.43) | LMNAHTTNPSR1TDP1KDM4E | |
| SCHEMBL19342481 | 0.78 | CHRNB2 (0.47) | LMNAHTTNPSR1TDP1KDM4E | |
| SCHEMBL19687558 | 0.74 | KDM4E (0.40) | LMNAHTTNPSR1TDP1KDM4E | |
| SCHEMBL23267299 | 0.73 | L3MBTL1 (0.55) | LMNANPSR1TDP1KDM4EMAPT | |
| SCHEMBL12893078 | 0.68 | CHRNB2 (0.47) | TDP1MAPTMAPK1CYP1A2CYP2C9 | |
| SCHEMBL19456536 | 0.68 | ALDH1A1 (0.50) | LMNANPSR1TDP1KDM4EMAPT | |
| SCHEMBL23267297 | 0.68 | ALDH1A1 (0.50) | LMNANPSR1TDP1KDM4EMAPT | |
| SCHEMBL7929602 | 0.67 | L3MBTL1 (0.59) | LMNAHTTTDP1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4218832-A2 | METHODS AND COMPOSITIONS FOR 18F-RADIOLABELING OF THE FIBRONECTIN TYPE (III) DOMAIN | Bristol-Myers Squibb Company (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-3223866-B1 | METHODS AND COMPOSITIONS FOR 18F-RADIOLABELING OF THE FIBRONECTIN TYPE (III) DOMAIN | BRISTOL MYERS SQUIBB CO (US) | 2023-03-08 | — | — | EP | disclosed |
| WO-2017210302-A1 | PET IMAGING WITH PD-L1 BINDING POLYPEPTIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-12-07 | — | — | WO | disclosed |
| WO-2017210335-A1 | IMAGING METHODS USING 18F-RADIOLABELED BIOLOGICS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-12-07 | — | — | WO | disclosed |