Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.36 |
| ▸ | PARG | Q86W56 | 2/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19687586 | 0.78 | MEN1 (0.46) | MEN1KMT2A | |
| SCHEMBL19687594 | 0.72 | ESR1 (0.40) | MEN1KMT2ARAB9A | |
| SCHEMBL19687591 | 0.72 | MEN1 (0.43) | MEN1KMT2ARAB9A | |
| SCHEMBL19687579 | 0.72 | RAB9A (0.33) | MEN1PARGKMT2ARAB9A | |
| SCHEMBL19687577 | 0.70 | MEN1 (0.46) | MEN1BRD4KMT2ACNR1CNR2 | |
| SCHEMBL19687581 | 0.69 | KDM4E (0.44) | MEN1KMT2ARAB9A | |
| SCHEMBL19687574 | 0.68 | PARG (0.40) | PARG | |
| SCHEMBL19687584 | 0.68 | PARG (0.39) | MEN1PARGKMT2ARAB9A | |
| SCHEMBL19301810 | 0.68 | PADI4 (0.39) | BRD4BAZ2ANSD2CNR1CNR2 | |
| SCHEMBL19687576 | 0.68 | RAB9A (0.35) | MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205972-A1 | SYSTEMS METHODS AND COMPOSITIONS FOR PREDICTING METASTASIS IN BLADDER CANCER | GENOMEDX BIOSCIENCES, INC. (CA) | 2017-12-07 | — | — | WO | disclosed |