Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19687591 | 0.78 | MEN1 (0.43) | MEN1KMT2AKDM4EMAPTTSHR | |
| SCHEMBL19687594 | 0.76 | ESR1 (0.40) | MEN1KMT2AMAPTRAB9APOLB | |
| SCHEMBL19687586 | 0.74 | MEN1 (0.46) | MEN1KMT2AKDM4EMAPTTSHR | |
| SCHEMBL20259682 | 0.74 | HRH1 (0.38) | MEN1KMT2AKDM4EMAPTTSHR | |
| SCHEMBL19687576 | 0.74 | RAB9A (0.35) | MEN1KMT2ATSHRRAB9A | |
| SCHEMBL19687598 | 0.74 | RAB9A (0.35) | KDM4EMAPTTSHRRAB9A | |
| SCHEMBL19687583 | 0.72 | MEN1 (0.43) | MEN1KMT2AKDM4EMAPTTSHR | |
| SCHEMBL19687584 | 0.72 | PARG (0.39) | MEN1KMT2ARAB9A | |
| SCHEMBL19687579 | 0.70 | RAB9A (0.33) | MEN1KMT2AKDM4EMAPTRAB9A | |
| SCHEMBL19687573 | 0.70 | MEN1 (0.37) | MEN1KMT2ARAB9ABRD4CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205972-A1 | SYSTEMS METHODS AND COMPOSITIONS FOR PREDICTING METASTASIS IN BLADDER CANCER | GENOMEDX BIOSCIENCES, INC. (CA) | 2017-12-07 | — | — | WO | disclosed |