Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | SCN7A | Q01118 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 9/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19687586 | 0.90 | MEN1 (0.46) | LMNAMEN1KMT2AMAPT | |
| SCHEMBL19687591 | 0.78 | MEN1 (0.43) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL19687577 | 0.76 | MEN1 (0.46) | POLBMEN1KMT2AMAPTRAB9A | |
| SCHEMBL19687581 | 0.75 | KDM4E (0.44) | LMNAPOLBMEN1KMT2ARAB9A | |
| SCHEMBL19687576 | 0.74 | RAB9A (0.35) | LMNAMEN1KMT2ARAB9A | |
| SCHEMBL19687598 | 0.74 | RAB9A (0.35) | LMNAMAPTRAB9A | |
| SCHEMBL19687579 | 0.73 | RAB9A (0.33) | MEN1KMT2AMAPTRAB9A | |
| SCHEMBL19687573 | 0.72 | MEN1 (0.37) | MEN1KMT2ARAB9A | |
| SCHEMBL19687583 | 0.72 | MEN1 (0.43) | LMNAPOLBMEN1KMT2AMAPT | |
| SCHEMBL19687584 | 0.72 | PARG (0.39) | MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205972-A1 | SYSTEMS METHODS AND COMPOSITIONS FOR PREDICTING METASTASIS IN BLADDER CANCER | GENOMEDX BIOSCIENCES, INC. (CA) | 2017-12-07 | — | — | WO | disclosed |