Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | KDM1A | O60341 | 10/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19687593 | 0.81 | POLB (0.41) | KDM4ERAB9ASCARB1 | |
| SCHEMBL19687577 | 0.78 | MEN1 (0.46) | MEN1KMT2AMAPTKDM4ERAB9A | |
| SCHEMBL19687594 | 0.78 | ESR1 (0.40) | MEN1KMT2AMAPTESR1ESR2 | |
| SCHEMBL19687578 | 0.78 | KDM1A (0.39) | MEN1KMT2AMAPTKDM4EKDM1A | |
| SCHEMBL19687583 | 0.77 | MEN1 (0.43) | MEN1KMT2AMAPTKDM4ERAB9A | |
| SCHEMBL19687586 | 0.76 | MEN1 (0.46) | MEN1KMT2AMAPTKDM4ETSHR | |
| SCHEMBL19687576 | 0.76 | RAB9A (0.35) | MEN1KMT2ARAB9ATSHR | |
| SCHEMBL19687598 | 0.76 | RAB9A (0.35) | MAPTKDM4ERAB9ATSHR | |
| SCHEMBL19295052 | 0.76 | MEN1 (0.39) | MEN1KMT2AMAPTKDM4ERAB9A | |
| SCHEMBL17596607 | 0.75 | GAA (0.37) | MEN1KMT2AMAPTKDM4EESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205972-A1 | SYSTEMS METHODS AND COMPOSITIONS FOR PREDICTING METASTASIS IN BLADDER CANCER | GENOMEDX BIOSCIENCES, INC. (CA) | 2017-12-07 | — | — | WO | disclosed |