Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19687594 | 0.90 | ESR1 (0.40) | MEN1MAPTLMNAKMT2A | |
| SCHEMBL19687591 | 0.76 | MEN1 (0.43) | MEN1MAPTTSHRKMT2AKDM4E | |
| SCHEMBL19687577 | 0.74 | MEN1 (0.46) | MEN1MAPTTSHRKMT2AHSD17B10 | |
| SCHEMBL19687581 | 0.73 | KDM4E (0.44) | MEN1TSHRLMNAKMT2AHSD17B10 | |
| SCHEMBL19687584 | 0.72 | PARG (0.39) | MEN1KMT2A | |
| SCHEMBL19687574 | 0.72 | PARG (0.40) | MAPT | |
| SCHEMBL19687576 | 0.72 | RAB9A (0.35) | MEN1TSHRLMNAKMT2A | |
| SCHEMBL19687579 | 0.71 | RAB9A (0.33) | MEN1MAPTKMT2AHSD17B10KDM4E | |
| SCHEMBL19687583 | 0.70 | MEN1 (0.43) | MEN1MAPTTSHRLMNAKMT2A | |
| SCHEMBL19687588 | 0.69 | PARG (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205972-A1 | SYSTEMS METHODS AND COMPOSITIONS FOR PREDICTING METASTASIS IN BLADDER CANCER | GENOMEDX BIOSCIENCES, INC. (CA) | 2017-12-07 | — | — | WO | disclosed |