Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19295052 | 0.81 | MEN1 (0.39) | KMT2AMEN1RAB9AGAAKDM4E | |
| SCHEMBL17596607 | 0.80 | GAA (0.37) | KMT2AMEN1RAB9AGAAKDM4E | |
| SCHEMBL19687587 | 0.80 | RAB9A (0.34) | KDM1ARAB9AHTTMAPTLMNA | |
| SCHEMBL19687591 | 0.78 | MEN1 (0.43) | KDM1AKMT2AMEN1RAB9AKDM4E | |
| SCHEMBL19300240 | 0.70 | MEN1 (0.33) | KMT2AMEN1GAAMAPTLMNA | |
| SCHEMBL1466312 | 0.69 | CFTR (0.47) | KDM1AKMT2AMEN1GAAKDM4E | |
| SCHEMBL13547925 | 0.69 | GAA (0.36) | KDM1AKMT2AMEN1GAAKDM4E | |
| SCHEMBL19687583 | 0.69 | MEN1 (0.43) | KMT2AMEN1RAB9AKDM4EMAPT | |
| SCHEMBL25726488 | 0.68 | PARG (0.30) | — | |
| SCHEMBL19687594 | 0.68 | ESR1 (0.40) | KMT2AMEN1RAB9AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205972-A1 | SYSTEMS METHODS AND COMPOSITIONS FOR PREDICTING METASTASIS IN BLADDER CANCER | GENOMEDX BIOSCIENCES, INC. (CA) | 2017-12-07 | — | — | WO | disclosed |