Sugi Predict

Sugi Predict / Compounds / SCHEMBL19690348

SCHEMBL19690348

SCHEMBL19690348

Cc1ccc(F)c(C)c1N

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.56
▸ CD44 P16070 1/20 0.39
▸ MAPT P10636 3/20 0.38
▸ ACHE P22303 1/20 0.36
▸ CYP3A4 P08684 4/20 0.36
▸ NOS3 P29474 2/20 0.36
▸ NOS2 P35228 2/20 0.36
▸ ALDH1A1 P00352 5/20 0.35
▸ LMNA P02545 2/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ GAA P10253 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ MEN1 O00255 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ TDP1 Q9NUW8 2/20 0.33
▸ CASP1 P29466 1/20 0.33
▸ DAO P14920 1/20 0.33
▸ TSHR P16473 3/20 0.32
▸ NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3670713 0.81 POLB (0.46) POLBCD44MAPTACHECYP3A4
SCHEMBL1548262 0.79 POLB (0.44) POLBCD44MAPTACHECYP3A4
SCHEMBL13999786 0.79 POLB (0.44) POLBCD44MAPTACHECYP3A4
SCHEMBL1085636 0.79 ALDH1A1 (0.39) POLBCD44ACHECYP3A4ALDH1A1
SCHEMBL394750 0.77 POLB (0.68) POLBCD44MAPTCYP3A4NOS3
Hydrochloric Acid SCHEMBL3213353 0.77 ALDH1A1 (0.37) POLBCD44MAPTCYP3A4ALDH1A1
SCHEMBL9380980 0.77 ALDH1A1 (0.39) POLBMAPTALDH1A1KDM4EGAA
SCHEMBL3725651 0.76 POLB (0.40) POLBCD44MAPTACHECYP3A4
SCHEMBL21624305 0.75 POLB (0.41) POLBCD44MAPTACHECYP3A4
SCHEMBL16550079 0.75 CA1 (0.32) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630516-B2 Compounds NRG THERAPEUTICS LTD. (GB) 2026-05-19 — — US disclosed
US-12497359-B2 Acrylamide derivatives NRG THERAPEUTICS LTD (GB) 2025-12-16 — — US disclosed
EP-4208442-B1 MPTP INHIBITORS NRG THERAPEUTICS LTD (GB) 2025-10-22 — — EP disclosed
US-20250179028-A1 ACRYLAMIDE COMPOUNDS NRG THERAPEUTICS LTD (GB) 2025-06-05 — — US disclosed
EP-4208448-B1 ACRYLAMIDE DERIVATIVES NRG THERAPEUTICS LTD (GB) 2025-04-23 — — EP disclosed
WO-2025038917-A1 HETEROARYL AMINE COMPOUNDS AND USES THEREOF XENON PHARMACEUTICALS INC. (CA) 2025-02-20 — — WO disclosed
WO-2025038920-A1 HETEROARYL AMINE COMPOUNDS AND USES THEREOF XENON PHARMACEUTICALS, INC. (CA) 2025-02-20 — — WO disclosed
EP-4486721-A1 ACRYLAMIDE COMPOUNDS NRG Therapeutics LTD (GB) 2025-01-08 — — EP disclosed
CN-118804911-A Acrylamide compound NRG治疗有限公司 2024-10-18 — — CN disclosed
US-20240067614-A1 NOVEL COMPOUNDS NRG THERAPEUTICS LTD. (GB) 2024-02-29 — — US disclosed
EP-3842433-A1 PYRIDONE-PYRIMIDINE DERIVATIVE ACTING AS KRASG12C MUTEIN INHIBITOR Medshine Discovery Inc. (CN) 2021-06-30 — — EP disclosed
US-20210147418-A1 Pyridone-Pyrimidine Derivative Acting As KRASG12C Mutein Inhibitor MEDSHINE DISCOVERY INC (CN) 2021-05-20 — — US disclosed
EP-3741756-A1 PYRIDONE-PYRIMIDINE DERIVATIVE ACTING AS KRASG12C MUTEIN INHIBITOR Medshine Discovery Inc. (CN) 2020-11-25 — — EP disclosed
EP-3468947-A1 FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES SciFluor Life Sciences, Inc. (US) 2019-04-17 — — EP disclosed
WO-2017214539-A1 FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES SCIFLUOR LIFE SCIENCES, INC. (US) 2017-12-14 — — WO disclosed
US-20170355679-A1 FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES SCIFLUOR LIFE SCIENCES, INC. 2017-12-14 — — US disclosed
US-20170355679-A1 FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES SCIFLUOR LIFE SCIENCES, INC. 2017-12-14 — — US disclosed
US-20170355679-A1 FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES SCIFLUOR LIFE SCIENCES, INC. 2017-12-14 — — US disclosed
WO-2017214539-A1 FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES SCIFLUOR LIFE SCIENCES, INC. (US) 2017-12-14 — — WO disclosed
CN-1073674-A Sterilant ROUSSEL UCLAF (FR) 1993-06-30 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630516-B2 Compounds CYP4B1, CYP1B1, NR4A1 POLB 3535/4885CD44 2440/4885MAPT 2453/4885
US-20240067614-A1 NOVEL COMPOUNDS CYP11B1, CYP11B2, CXCR2 POLB 3892/4885CD44 2782/4885MAPT 2596/4885
US-20250179028-A1 ACRYLAMIDE COMPOUNDS ACR, CCNI, FANCI POLB 2461/4885CD44 2324/4885MAPT 1371/4885
US-20170355679-A1 FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES KCNQ2, KCNQ1, KCNQ3 POLB 4643/4885CD44 4834/4885MAPT 2123/4885
US-12497359-B2 Acrylamide derivatives ACR, GSTA2, GSTA1 POLB 2514/4885CD44 1934/4885MAPT 1784/4885
US-20210147418-A1 Pyridone-Pyrimidine Derivative Acting As KRASG12C Mutein Inhibitor KRAS, NRAS, MSH2 POLB 286/4885CD44 4567/4885MAPT 3175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.