Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 8/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.69 |
| ▸ | POLB | P06746 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | DDX3X | O00571 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30069319 | 1.00 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| 3-Nitroaniline SCHEMBL3972851 | 0.92 | RAB9A (0.61) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL27833966 | 0.90 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL5141415 | 0.89 | MEN1 (0.75) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL4262411 | 0.88 | HDAC1 (0.58) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL4749088 | 0.88 | L3MBTL1 (0.71) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL4749309 | 0.85 | L3MBTL1 (0.76) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL4262414 | 0.85 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL9427754 | 0.84 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL6069337 | 0.84 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101508674-A | Benazepine-2-ketone compound containing ethylene imine ring, preparation and application thereof | UNIV DONGHUA (CN) | 2009-08-19 | — | — | CN | claimed |
| CN-118126030-A | Preparation method of pyrazoline-1, 3, 4-oxadiazole thioacetamide derivative and application of pyrazoline-1, 3, 4-oxadiazole thioacetamide derivative as pesticide | 贵州大学 | 2024-06-04 | — | — | CN | disclosed |
| CN-115322163-B | Dicarboxamido tetrazine compound as VEGFR-2 inhibitor and preparation and application thereof | 浙江工业大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-115322163-A | Di-methylamino-s-tetrazine compound as VEGFR-2 inhibitor and preparation and application thereof | 浙江工业大学 | 2022-11-11 | — | — | CN | disclosed |
| CN-108558810-B | Flavonoid derivative with ROCK kinase inhibition effect | 四川大学 | 2021-09-21 | — | — | CN | disclosed |
| EP-2334301-B1 | MACROCYCLICS PYRIMIDINES AS AURORA KINASE INHIBITORS | MERCK SERONO SA (CH) | 2018-02-14 | — | — | EP | disclosed |
| US-8815872-B2 | Macrocyclics pyrimidines as aurora kinase inhibitors | MERCK PATENT GMBH (DE) | 2014-08-26 | — | — | US | disclosed |
| US-8815872-B2 | Macrocyclics pyrimidines as aurora kinase inhibitors | MERCK PATENT GMBH (DE) | 2014-08-26 | — | — | US | disclosed |
| US-8815872-B2 | Macrocyclics pyrimidines as aurora kinase inhibitors | MERCK PATENT GMBH (DE) | 2014-08-26 | — | — | US | disclosed |
| CN-102159564-B | Arylsulfonamide compounds and their use as 5-HT6 ligands | SUVEN LIFE SCIENCES LTD | 2014-06-18 | — | — | CN | disclosed |
| US-5393735-A | N-(halo-oxy-)phenyl substituted cyclic imides | ROHM AND HAAS COMPANY (US) | 1995-02-28 | — | — | US | disclosed |
| US-5382682-A | Nitroanilides and their preparation | EASTMAN KODAK COMPANY (US) | 1995-01-17 | — | — | US | disclosed |
| EP-0425345-B1 | Keratinic fibres dyeing process with amino-indoles, composition and use devices | OREAL (FR) | 1994-09-14 | — | — | EP | disclosed |
| US-5254135-A | Applying indole dye, developing with oxidizing system | L'OREAL (FR) | 1993-10-19 | — | — | US | disclosed |
| EP-0517871-A1 | NOVEL NITROANILIDES AND THEIR PREPARATION. | KODAK LTD (GB) | 1992-12-16 | — | — | EP | disclosed |
| WO-1992011230-A1 | NOVEL NITROANILIDES AND THEIR PREPARATION | KODAK LIMITED (GB) | 1992-07-09 | — | — | WO | disclosed |
| CN-1051669-A | With the method for amino indole dyeing keratinous fibres, compositions and facilities and equipments | OREAL (FR) | 1991-05-29 | — | — | CN | disclosed |
| EP-0425345-A1 | Keratinic fibres dyeing process with amino-indoles, composition and use devices | L'OREAL (FR) | 1991-05-02 | — | — | EP | disclosed |
| CN-1049846-A | Glutarimide with weeding activity | ROHM & HAAS (US) | 1991-03-13 | — | — | CN | disclosed |
| EP-0415642-A1 | Glutarimides | ROHM AND HAAS COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |