Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.34 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1963777 | 0.86 | ALDH1A1 (0.40) | MAPK1KDM4ETSHRALDH1A1LMNA | |
| SCHEMBL1969215 | 0.77 | CYP3A4 (0.34) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4371738 | 0.68 | CYP1A2 (0.44) | MAPK1KDM4ETSHRALDH1A1LMNA | |
| SCHEMBL7398766 | 0.67 | HPGD (0.37) | MAPK1KDM4ETSHRALDH1A1LMNA | |
| SCHEMBL8562993 | 0.66 | ALDH1A1 (0.43) | MAPK1KDM4ETSHRALDH1A1LMNA | |
| SCHEMBL5809049 | 0.65 | ALDH1A1 (0.47) | MAPK1KDM4ETSHRALDH1A1LMNA | |
| SCHEMBL2472768 | 0.64 | ALDH1A1 (0.41) | MAPK1KDM4ETSHRALDH1A1LMNA | |
| SCHEMBL1275935 | 0.64 | ALDH1A1 (0.46) | MAPK1KDM4ETSHRALDH1A1LMNA | |
| SCHEMBL9137641 | 0.63 | ALDH1A1 (0.65) | KDM4ETSHRALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL1417761 | 0.63 | ALDH1A1 (0.45) | MAPK1KDM4ETSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334668-A1 | PROCESS FOR PREPARING OLMESARTAN MEDOXOMIL INTERMEDIATE | Krka Tovarna Zdravil, D.D., Novo Mesto (SI) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010026255-A1 | PROCESS FOR PREPARING OLMESARTAN MEDOXOMIL INTERMEDIATE | KRKA, TOVARNA ZDRAVIL, D.D., NOVO MESTO (SI) | 2010-03-11 | — | — | WO | disclosed |