Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.39 |
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PTAFR | P25105 | 2/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19699124 | 0.80 | HTR1A (0.47) | DRD2HTR1AHTR2AHRH1CHRM2 | |
| SCHEMBL25596768 | 0.73 | HTR1A (0.45) | DRD2HTR1AHTR2AHRH1CHRM2 | |
| SCHEMBL12573365 | 0.73 | ADAM17 (0.48) | DRD2HTR1AHTR2AHRH1CHRM2 | |
| SCHEMBL29431445 | 0.73 | ADAM17 (0.48) | DRD2HTR1AHTR2AHRH1CHRM2 | |
| SCHEMBL27252004 | 0.71 | HTR1A (0.48) | DRD2HTR1AHTR2AHRH1CHRM2 | |
| SCHEMBL31484024 | 0.71 | VNN1 (0.33) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL3399553 | 0.70 | HTR1A (0.48) | DRD2HTR1AHTR2AADAM17 | |
| SCHEMBL803066 | 0.70 | HTR1A (0.40) | DRD2HTR1AHTR2AHRH1CHRM2 | |
| SCHEMBL7711222 | 0.69 | MTNR1A (0.44) | DRD2HTR1AHTR2AHRH1CHRM2 | |
| SCHEMBL4912110 | 0.69 | TSHR (0.43) | DRD2HTR1AHTR2AHRH1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611925-B | HPK1 inhibitors and uses thereof | 轩竹生物科技股份有限公司 | 2025-04-08 | — | — | CN | disclosed |