Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17657914 | 0.81 | PTGER4 (0.43) | PTGER4MAPTKDM4EHCRTR1CASP1 | |
| SCHEMBL17718403 | 0.76 | TDP1 (0.50) | PTGER4MAPTKDM4EHCRTR1CASP1 | |
| SCHEMBL29878719 | 0.73 | PTGER4 (0.49) | PTGER4MAPTKDM4EHCRTR1CASP1 | |
| SCHEMBL8505144 | 0.73 | PTGER4 (0.49) | PTGER4MAPTKDM4EHCRTR1CASP1 | |
| SCHEMBL1921296 | 0.72 | KDM4E (0.53) | PTGER4MAPTKDM4EHCRTR1CASP1 | |
| SCHEMBL7603554 | 0.72 | RAB9A (0.52) | PTGER4MAPTKDM4EHCRTR1CASP1 | |
| SCHEMBL26631782 | 0.71 | NPSR1 (0.46) | PTGER4MAPTKDM4EHCRTR1CASP1 | |
| SCHEMBL9979911 | 0.69 | KDM4E (0.50) | PTGER4MAPTKDM4EHCRTR1CASP1 | |
| SCHEMBL7796764 | 0.69 | ALDH1A1 (0.55) | PTGER4MAPTKDM4EHCRTR1CASP1 | |
| SCHEMBL21979134 | 0.68 | NQO2 (0.61) | MAPTKDM4EHCRTR1CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017214269-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | INFINITY PHARMACEUTICALS, INC. (US) | 2017-12-14 | — | — | WO | disclosed |