Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | BCL9 | O00512 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7434055 | 0.98 | CYP3A4 (0.50) | CYP3A4TP53TSHRALDH1A1BCL9 | |
| SCHEMBL27931318 | 0.90 | TSHR (0.54) | CYP3A4TP53TSHRALDH1A1ACHE | |
| SCHEMBL4270896 | 0.89 | TSHR (0.56) | CYP3A4TP53TSHRALDH1A1ACHE | |
| SCHEMBL9417626 | 0.88 | TSHR (0.59) | CYP3A4TP53TSHRALDH1A1KMT2A | |
| SCHEMBL421378 | 0.88 | BCL9 (0.53) | ALDH1A1BCL9CTNNB1ACHEKMT2A | |
| SCHEMBL360724 | 0.86 | ACHE (0.61) | CYP3A4TP53TSHRALDH1A1ACHE | |
| Methane SCHEMBL28871512 | 0.85 | ACHE (0.59) | CYP3A4TP53TSHRALDH1A1ACHE | |
| Hydrochloric Acid SCHEMBL27650513 | 0.85 | ACHE (0.59) | CYP3A4TP53TSHRALDH1A1ACHE | |
| SCHEMBL4810160 | 0.83 | LMNA (0.62) | ALDH1A1BCL9CTNNB1ACHEKMT2A | |
| SCHEMBL13721468 | 0.82 | BCL9 (0.47) | ALDH1A1BCL9CTNNB1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103495340-B | The method of SOx in compound alcamines solution removal gas | BEIJING BOYUAN HENGSHENG HIGH-TECHNOLOGY CO.,LTD. (CN) | 2015-11-18 | — | — | CN | claimed |
| CN-103495340-A | Method of removing SOx in gas by compound alkanolamine solution | BEIJING BOYUAN HENGSHENG HIGH TECHNOLOGY CO LTD | 2014-01-08 | — | — | CN | claimed |
| US-7521216-B2 | Nitrilases and methods for making and using them | VERENIUM CORPORATION (US) | 2009-04-21 | — | — | US | claimed |
| US-20030124698-A1 | Which stereoselectively hydrolyze nitrites or cyanohydrins into acids and ammonia | DIVERSA CORPORATION | 2003-07-03 | — | — | US | claimed |
| US-5512548-A | CHOLESTERYL ESTER TRANSFER PROTEIN | SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH (US) | 1996-04-30 | — | — | US | claimed |
| CN-103980618-B | Single layer and multilayer blown film | 巴斯夫欧洲公司 | 2018-11-13 | — | — | CN | disclosed |
| US-9828594-B2 | Nitrilases, nucleic acids encoding them and methods for making and using them | BASF ENZYMES LLC (US) | 2017-11-28 | — | — | US | disclosed |
| US-20160355801-A1 | NITRILASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | VERENIUM CORPORATION | 2016-12-08 | — | — | US | disclosed |
| CN-102712676-B | There is the peptidomimetic that the template of CCR10 antagonistic activity is fixing | 波利弗尔股份公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-102844327-B | Template-fixed peptidomimetics with CXCR7 modulatory activity | 波利弗尔股份公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-105960399-A | Epoxyketone compounds for enzyme inhibition | 宁波圣健生物医药科技有限公司 | 2016-09-21 | — | — | CN | disclosed |
| US-9315792-B2 | Nitrilases, nucleic acids encoding them and methods for making and using them | BASF ENZYMES LLC (US) | 2016-04-19 | — | — | US | disclosed |
| CN-1150195-C | Bicyclic nitrogen heterocycles | - | 2004-05-19 | — | — | CN | disclosed |
| US-20040014195-A1 | Nitrilases, nucleic acids encoding them and methods for making and using them | DIVERSA CORPORATION (US) | 2004-01-22 | — | — | US | disclosed |
| US-20040002147-A1 | Nitrilases | DIVERSA CORPORATION | 2004-01-01 | — | — | US | disclosed |
| CN-1450894-A | Phenylethylamines and fused ring variants as prodrugs of catecholamines and uses thereof | AXON BIOCHEMICALS BV (NL) | 2003-10-22 | — | — | CN | disclosed |
| US-20030124698-A1 | Which stereoselectively hydrolyze nitrites or cyanohydrins into acids and ammonia | DIVERSA CORPORATION | 2003-07-03 | — | — | US | disclosed |
| CN-1324360-A | Bicyclic nitrogen heterocycles | HOFFMANN LA ROCHE (CH) | 2001-11-28 | — | — | CN | disclosed |
| CN-1319090-A | Novel substuted indolimones, their preparation process and use as medicine | BOEHRINGER INGELHEIM PHARMA (DE) | 2001-10-24 | — | — | CN | disclosed |
| EP-0373881-A2 | Process for preparing optically active 2-oxoimidazolidine derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1990-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014195-A1 | Nitrilases, nucleic acids encoding them and methods for making and using them | RNGTT, NSUN2, NSUN3 | CYP3A4 3130/4885TP53 1317/4885TSHR 4156/4885 |
| US-20040002147-A1 | Nitrilases | RNGTT, DNTT, NOP2 | CYP3A4 1756/4885TP53 978/4885TSHR 4001/4885 |
| US-20030124698-A1 | Which stereoselectively hydrolyze nitrites or cyanohydrins into acids and ammonia | NIT2, DNPH1, ASNS | CYP3A4 1629/4885TP53 2212/4885TSHR 4562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.