SCHEMBL1970472

SCHEMBL1970472

N#CCCc1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP9 P14780 1/20 0.51
MMP13 P45452 1/20 0.51
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
LMNA P02545 1/20 0.43
CA2 P00918 9/20 0.42
CA1 P00915 7/20 0.42
CA12 O43570 6/20 0.42
CA4 P22748 5/20 0.42
TSHR P16473 4/20 0.42
ALDH1A1 P00352 1/20 0.42
NT5E P21589 1/20 0.42
CA6 P23280 2/20 0.40
CA5A P35218 2/20 0.40
CA7 P43166 2/20 0.40
CA9 Q16790 2/20 0.40
CA14 Q9ULX7 2/20 0.40
CA5B Q9Y2D0 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22769624 0.89 CA2 (0.43) MMP9MMP13LMNACA2CA1
SCHEMBL11583429 0.81 LMNA (0.56) LMNACA2CA1CA12CA4
SCHEMBL7894078 0.81 LMNA (0.43) MMP9MMP13LMNACA2CA1
SCHEMBL9684079 0.81 CA2 (0.63) CA2CA1CA12CA4CA6
SCHEMBL11293386 0.80 LMNA (0.46) MEN1KMT2ALMNACA2CA1
SCHEMBL23632132 0.79 PSIP1 (0.53) MMP9MMP13MEN1KMT2ACA2
SCHEMBL8764230 0.78 MEN1 (0.64) MMP9MMP13MEN1KMT2ACA2
SCHEMBL5560243 0.78 CA2 (0.42) MMP9MMP13LMNACA2CA1
SCHEMBL30446884 0.77 CA2 (0.57) LMNACA2CA1CA12CA4
SCHEMBL16350024 0.75 LMNA (0.50) LMNACA2CA1CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8864894-B2 Resist underlayer film forming composition containing silicone having onium group NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-10-21 US disclosed
EP-2336256-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM WITH ONIUM GROUP Nissan Chemical Industries, Ltd. (JP) 2011-06-22 EP disclosed
US-20110143149-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION CONTAINING SILICONE HAVING ONIUM GROUP NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2011-06-16 US disclosed
US-4260555-A CONDENSING A CYANOALKYL PHENYLSULFONATE WITH OXIMINOARYLNITRILE CIBA-GEIGY CORPORATION (US) 1981-04-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110143149-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION CONTAINING SILICONE HAVING ONIUM GROUP SRR, KDM2B, MSR1 MMP9 1084/4885MMP13 3536/4885MEN1 1606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.