Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 6/20 | 0.40 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19692418 | 0.87 | NOS2 (0.42) | ALOX15NPSR1LMNAMEN1NPC1 | |
| SCHEMBL20995966 | 0.84 | BTK (0.42) | MERTK | |
| SCHEMBL336704 | 0.83 | ELANE (0.36) | OPRM1OPRK1OGFRL1LMNAALDH1A1 | |
| SCHEMBL1725407 | 0.83 | ALDH1A1 (0.48) | LMNANPC1ALDH1A1RAB9AMAPT | |
| SCHEMBL3846399 | 0.76 | LMNA (0.38) | LMNAALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL335976 | 0.76 | LMNA (0.43) | ALOX15OPRK1LMNAMEN1ALDH1A1 | |
| SCHEMBL19707058 | 0.74 | CRHR1 (0.39) | MERTK | |
| SCHEMBL496337 | 0.73 | RIPK1 (0.49) | ALDH1A1AXLMERTKKDM4E | |
| SCHEMBL496141 | 0.73 | POLB (0.54) | NPSR1RAB9AAXLMERTK | |
| SCHEMBL3841789 | 0.72 | KCNA3 (0.42) | LMNAMERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017211759-A1 | NEW ANTIBACTERIAL COMPOUNDS | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2017-12-14 | — | — | WO | disclosed |
| WO-2017211760-A1 | NEW ANTIBACTERIAL COMPOUNDS | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2017-12-14 | — | — | WO | disclosed |