Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGAV | P06756 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | PCNA | P12004 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19708683 | 0.75 | THRB (0.57) | ITGB3ITGAVTHRATHRBPPARG | |
| SCHEMBL19708684 | 0.63 | ITGB3 (0.55) | ITGB3ITGAVTHRATHRBPPARG | |
| SCHEMBL19677575 | 0.63 | ITGB3 (0.61) | ITGB3ITGAVTHRATHRBPPARG | |
| SCHEMBL9914065 | 0.61 | BRD4 (0.39) | LMNAPOLBGABRB2HSD17B10 | |
| SCHEMBL19677591 | 0.61 | ITGB3 (0.71) | ITGB3ITGAVTHRATHRBPPARG | |
| SCHEMBL25661181 | 0.61 | NPC1 (0.44) | CYP1A2POLBCYP2C9HPGD | |
| SCHEMBL23984251 | 0.61 | ITGB3 (0.52) | ITGB3ITGAVTHRATHRBPPARG | |
| SCHEMBL24063119 | 0.60 | THRB (0.47) | ITGB3ITGAVTHRATHRBPPARG | |
| SCHEMBL4273195 | 0.58 | FFAR1 (0.54) | ITGB3ITGAVTHRATHRBPPARG | |
| SCHEMBL19219143 | 0.56 | RXRA (0.57) | RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017214299-A1 | NON-CLEAVABLE POLYMER CONJUGATED WITH αvβ3 INTEGRIN THYROID ANTAGONISTS | NANOPHARMACEUTICALS, LLC (US) | 2017-12-14 | — | — | WO | disclosed |