Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13157445 | 0.92 | TSHR (0.45) | TSHRHTTALOX15L3MBTL1ALDH1A1 | |
| SCHEMBL13108110 | 0.92 | TSHR (0.41) | TSHRHTTALOX15L3MBTL1ALDH1A1 | |
| SCHEMBL11964603 | 0.91 | USP2 (0.44) | ALDH1A1ARMEN1KMT2A | |
| SCHEMBL19720294 | 0.88 | TRPV4 (0.34) | TSHRCYP19A1HPGDLMNAAR | |
| SCHEMBL15197176 | 0.87 | ALDH1A1 (0.45) | ALDH1A1ALKLMNAMEN1KMT2A | |
| SCHEMBL19720319 | 0.85 | POLB (0.40) | TSHRALDH1A1CYP19A1POLBHPGD | |
| SCHEMBL15197175 | 0.85 | CNR1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL19720318 | 0.84 | PKM (0.38) | ALDH1A1CYP19A1RAB9AAR | |
| SCHEMBL15197169 | 0.84 | LMNA (0.44) | L3MBTL1ALDH1A1ALKLMNAMEN1 | |
| SCHEMBL11964602 | 0.84 | TGM2 (0.43) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2749554-B1 | 2,5-disubstituted arylsulfonamide CCR3 antagonists | SMA THERAPEUTICS INC (US) | 2017-12-20 | — | — | EP | disclosed |