SCHEMBL19720997

SCHEMBL19720997

CC(C)(C)[Si](OS)(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.34
ALDH1A1 P00352 1/20 0.32
ALOX15 P16050 1/20 0.32
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
CYP3A4 P08684 1/20 0.30
HTT P42858 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
SMYD2 Q9NRG4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL79874 0.81 MAPK1 (0.37) MAPK1ALDH1A1ALOX15ESR1ESR2
SCHEMBL15888456 0.81 MAPK1 (0.37) MAPK1ALDH1A1ALOX15ESR1ESR2
SCHEMBL704188 0.79 MAPK1 (0.36) MAPK1ALDH1A1ALOX15ESR1ESR2
SCHEMBL4835281 0.77 MAPK1 (0.34) MAPK1ALDH1A1ALOX15ESR1ESR2
SCHEMBL31318429 0.77 MAPK1 (0.34) MAPK1ALDH1A1ALOX15ESR1ESR2
SCHEMBL18924906 0.77 ALDH1A1 (0.41) MAPK1ALDH1A1ALOX15ESR1ESR2
SCHEMBL707572 0.77 MAPK1 (0.34) MAPK1ALDH1A1ALOX15ESR1ESR2
SCHEMBL707090 0.77 MAPK1 (0.34) MAPK1ALDH1A1ALOX15ESR1ESR2
SCHEMBL26964680 0.77 MAPK1 (0.34) MAPK1ALDH1A1ALOX15ESR1ESR2
Hydroxyamine SCHEMBL9901947 0.76 ALDH1A1 (0.35) MAPK1ALDH1A1ALOX15ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2783731-B1 Process for designing rugged pattern on golf ball surface DUNLOP SPORTS CO LTD (JP) 2017-12-20 EP disclosed