Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20954476 | 0.83 | TAAR1 (0.34) | MAPK1ALDH1A1ALOX15 | |
| SCHEMBL15888456 | 0.81 | MAPK1 (0.37) | MAPK1ALDH1A1ALOX15TSHRESR1 | |
| SCHEMBL430199 | 0.81 | MAPK1 (0.37) | MAPK1ALDH1A1ALOX15TSHRHSD17B10 | |
| SCHEMBL79874 | 0.81 | MAPK1 (0.37) | MAPK1ALDH1A1ALOX15ESR1ESR2 | |
| SCHEMBL26353201 | 0.79 | TAAR1 (0.41) | MAPK1CYP3A4HTTSMN1; SMN2SMYD2 | |
| SCHEMBL703604 | 0.79 | ESR1 (0.37) | MAPK1ALDH1A1ALOX15TSHRHSD17B10 | |
| SCHEMBL704188 | 0.79 | MAPK1 (0.36) | MAPK1ALDH1A1ALOX15ESR1ESR2 | |
| SCHEMBL7251927 | 0.78 | ALDH1A1 (0.39) | MAPK1ALDH1A1ALOX15TSHRESR1 | |
| SCHEMBL30335459 | 0.78 | CYP3A4 (0.30) | CYP3A4HTTSMN1; SMN2SMYD2 | |
| SCHEMBL28978518 | 0.78 | NPSR1 (0.33) | ALDH1A1ALOX15TSHRESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2977409-B2 | GLASS-FIBER-REINFORCED POLYCARBONATE RESIN COMPOSITION | TEIJIN LTD (JP) | 2022-12-07 | — | — | EP | disclosed |
| US-20180141889-A1 | METHODS OF SYNTHESIZING A PROSTACYCLIN ANALOG | CAYMAN CHEMICAL COMPANY INCORPORATED (US) | 2018-05-24 | — | — | US | disclosed |
| US-20180118656-A1 | AMINE SALTS OF A PROSTACYCLIN ANALOG | CAYMAN CHEMICAL COMPANY INCORPORATED (US) | 2018-05-03 | — | — | US | disclosed |
| US-9908834-B2 | Methods of synthesizing a prostacyclin analog | CAYMAN CHEMICAL COMPANY INCORPORATED (US) | 2018-03-06 | — | — | US | disclosed |
| US-9890104-B2 | Amine salts of a prostacyclin analog | CAYMAN CHEMICAL COMPANY INCORPORATED (US) | 2018-02-13 | — | — | US | disclosed |
| US-20170295793-A1 | Photodynamic Insecticides | NATIONAL TAIWAN UNIVERSITY (TW) | 2017-10-19 | — | — | US | disclosed |
| US-20170297995-A1 | METHODS OF SYNTHESIZING A PROSTACYCLIN ANALOG | CAYMAM CHEMICAL COMPANY INCORPORATED (US) | 2017-10-19 | — | — | US | disclosed |
| US-20160289158-A1 | Amine Salts of a Prostacyclin Analog | CAYMAN CHEMICAL COMPANY INCORPORATED (US) | 2016-10-06 | — | — | US | disclosed |
| US-20150315114-A1 | Methods of Synthesizing a Prostacyclin Analog | CAYMAN CHEMICAL COMPANY INCORPORATED | 2015-11-05 | — | — | US | disclosed |
| US-8124239-B2 | Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same | FUJITSU LIMITED (JP) | 2012-02-28 | — | — | US | disclosed |
| US-20100155121-A1 | SILICA FILM FORMING MATERIAL, SILICA FILM AND METHOD OF MANUFACTURING THE SAME, MULTILAYER WIRING STRUCTURE AND METHOD OF MANUFACTURING THE SAME, AND SEMICONDUCTOR DEVICE AND METHOD OF MANUFACTURING THE SAME | FUJITSU LIMITED (JP) | 2010-06-24 | — | — | US | disclosed |
| US-7659357-B2 | Precursor organosilicon polymer of 1,2-Bis(dimethylethoxysilyl)ethane, 1,4-bis(dimethylethoxysilyl)benzene, tetraethoxysilane, methyltriethoxysilane, phenyltriethoxysilane; dielectric (DE) films having etching/chemical/moisture resistance; adhesion; low DE constant; minimal wiring delay; high speed | FUJITSU LIMITED (JP) | 2010-02-09 | — | — | US | disclosed |
| US-20070026689-A1 | Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same | FUJITSU LIMITED (JP) | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160289158-A1 | Amine Salts of a Prostacyclin Analog | PTGIS, PTGIR, PTGER1 | MAPK1 1373/4885ALDH1A1 519/4885ALOX15 128/4885 |
| US-20170295793-A1 | Photodynamic Insecticides | PPOX, DDT, CRY1 | MAPK1 4869/4885ALDH1A1 573/4885ALOX15 2243/4885 |
| US-20150315114-A1 | Methods of Synthesizing a Prostacyclin Analog | PTGIS, CYP11B2, CYP11B1 | MAPK1 1109/4885ALDH1A1 257/4885ALOX15 101/4885 |
| US-20180141889-A1 | METHODS OF SYNTHESIZING A PROSTACYCLIN ANALOG | PTGIS, CYP11B1, CYP11B2 | MAPK1 1321/4885ALDH1A1 278/4885ALOX15 82/4885 |
| US-20180118656-A1 | AMINE SALTS OF A PROSTACYCLIN ANALOG | PTGIS, PTGIR, PTGER1 | MAPK1 1373/4885ALDH1A1 519/4885ALOX15 128/4885 |
| US-20170297995-A1 | METHODS OF SYNTHESIZING A PROSTACYCLIN ANALOG | PTGIS, CYP11B2, CYP11B1 | MAPK1 1109/4885ALDH1A1 257/4885ALOX15 101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.