Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.57 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3748204 | 0.75 | HDAC6 (0.60) | HPGDNPC1RAB9AHDAC6ALDH1A1 | |
| SCHEMBL18573454 | 0.73 | HDAC6 (0.55) | HPGDNPC1RAB9AHDAC6ALDH1A1 | |
| SCHEMBL3086968 | 0.72 | HDAC6 (0.85) | HPGDNPC1RAB9AHDAC6ALDH1A1 | |
| SCHEMBL18573453 | 0.71 | RAB9A (0.60) | HPGDNPC1RAB9AHDAC6ALDH1A1 | |
| SCHEMBL18573590 | 0.70 | NPC1 (0.62) | HPGDNPC1RAB9AHDAC6ALDH1A1 | |
| SCHEMBL21230173 | 0.68 | ALDH1A1 (0.39) | HPGDNPC1RAB9AHDAC6ALDH1A1 | |
| SCHEMBL18573642 | 0.68 | NPC1 (0.63) | HPGDNPC1RAB9AHDAC6ALDH1A1 | |
| SCHEMBL6246675 | 0.68 | HDAC6 (0.72) | HPGDNPC1RAB9AHDAC6ALDH1A1 | |
| SCHEMBL21230117 | 0.68 | ALDH1A1 (0.38) | HPGDNPC1RAB9AHDAC6ALDH1A1 | |
| SCHEMBL25093334 | 0.67 | SMN1; SMN2 (0.44) | HPGDNPC1RAB9AHDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10350192-B2 | Lactate dehydrogenase inhibitor and antiepileptic drug containing the same | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2019-07-16 | — | — | US | disclosed |
| US-20180015068-A1 | LACTATE DEHYDROGENASE INHIBITOR AND ANTIEPILEPTIC DRUG CONTAINING THE SAME | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2018-01-18 | — | — | US | disclosed |
| EP-3257510-A1 | LACTATE DEHYDROGENASE INHIBITOR AND ANTIEPILEPTIC DRUG CONTAINING SAME | National University Corporation Okayama University (JP) | 2017-12-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180015068-A1 | LACTATE DEHYDROGENASE INHIBITOR AND ANTIEPILEPTIC DRUG CONTAINING THE SAME | LDHA, LDHB, ALDH5A1 | HPGD 117/4885GABRA1 706/4885GABRB2 439/4885 |
| US-10350192-B2 | Lactate dehydrogenase inhibitor and antiepileptic drug containing the same | LDHA, LDHB, ALDH5A1 | HPGD 117/4885GABRA1 706/4885GABRB2 439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.