Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.39 |
| ▸ | APEX1 | P27695 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16727672 | 0.93 | THRB (0.48) | ALDH1A1THRBTSHRCHRM5CHRM1 | |
| Methacrylic Acid SCHEMBL14894474 | 0.90 | THRB (0.46) | ALDH1A1THRBTSHRCHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL252608 | 0.84 | CHRM5 (0.57) | ALDH1A1THRBTSHRCHRM5CHRM1 | |
| SCHEMBL1984343 | 0.84 | THRB (0.50) | ALDH1A1THRBTSHRCHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL21611322 | 0.84 | THRB (0.50) | ALDH1A1THRBTSHRCHRM5CHRM1 | |
| SCHEMBL1972023 | 0.84 | TSHR (0.60) | ALDH1A1THRBTSHRCHRM5CHRM1 | |
| SCHEMBL3092716 | 0.83 | ALDH1A1 (0.46) | ALDH1A1THRBTSHRCHRM5CHRM1 | |
| SCHEMBL1291892 | 0.80 | ALDH1A1 (0.71) | ALDH1A1THRBTSHRCHRM5CHRM1 | |
| Methacrylic Acid SCHEMBL7553425 | 0.78 | ALDH1A1 (0.62) | ALDH1A1THRBTSHRAPEX1POLB | |
| Hydrochloric Acid SCHEMBL28569529 | 0.76 | TSHR (0.58) | ALDH1A1THRBTSHRCHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1855643-B1 | DYEING OF IN PARTICULAR HUMAN KERATIN MATERIALS BY DRY THERMAL TRANSFER OF A DIRECT DYE, COMPOSITION COMPRISING THE SAID DYE AND ITS METHOD OF PREPARATION | OREAL (FR) | 2011-08-03 | — | — | EP | disclosed |
| EP-1855638-B1 | DYEING OF IN PARTICULAR HUMAN KERATIN MATERIALS BY DRY THERMAL TRANSFER OF A DIRECT ANTHRAQUINONE DYE, COMPOSITION COMPRISING THE SAID DYE AND ITS METHOD OF PREPARATION | OREAL (FR) | 2011-06-22 | — | — | EP | disclosed |
| US-7722680-B2 | Dyeing of human keratin materials by dry thermal transfer of a direct dye, composition comprising the said dye and its method of preparation | L'OREAL S.A. (FR) | 2010-05-25 | — | — | US | disclosed |
| US-7651535-B2 | Dyeing of in particular human keratin materials by dry thermal transfer of a direct anthraquinone dye, composition comprising the said dye and its method of preparation | L'OREAL S.A. (FR) | 2010-01-26 | — | — | US | disclosed |
| US-7645304-B2 | Dyeing of in particular human keratin materials by dry thermal transfer of a direct azomethine dye, composition comprising the said dye and its method of preparation | L'OREAL S.A. (FR) | 2010-01-12 | — | — | US | disclosed |
| US-20080168608-A1 | Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Anthraquinone Dye, Composition Comprising the Said Dye and Its Method of Preparation | L'OREAL S.A. (FR) | 2008-07-17 | — | — | US | disclosed |
| US-20080148496-A1 | Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Dye, Composition Comprising the Said Dye and Its Method of Preparation | L'OREAL S.A. (FR) | 2008-06-26 | — | — | US | disclosed |
| US-20080120792-A1 | Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Azomethine Dye, Composition Comprising the Said Dye and its Method of Preparation | L'OREAL S.A. (FR) | 2008-05-29 | — | — | US | disclosed |
| EP-1855643-A1 | DYEING OF IN PARTICULAR HUMAN KERATIN MATERIALS BY DRY THERMAL TRANSFER OF A DIRECT DYE, COMPOSITION COMPRISING THE SAID DYE AND ITS METHOD OF PREPARATION | L'OREAL (FR) | 2007-11-21 | — | — | EP | disclosed |
| EP-1855636-A1 | DYEING OF IN PARTICULAR HUMAN KERATIN MATERIALS BY DRY THERMAL TRANSFER OF A DIRECT AZOMETHINE DYE, COMPOSITION COMPRISING THE SAID DYE AND ITS METHOD OF PREPARATION | L'OREAL (FR) | 2007-11-21 | — | — | EP | disclosed |
| EP-1855638-A1 | DYEING OF IN PARTICULAR HUMAN KERATIN MATERIALS BY DRY THERMAL TRANSFER OF A DIRECT ANTHRAQUINONE DYE, COMPOSITION COMPRISING THE SAID DYE AND ITS METHOD OF PREPARATION | L'Oréal (FR) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006089807-A1 | DYEING OF IN PARTICULAR HUMAN KERATIN MATERIALS BY DRY THERMAL TRANSFER OF A DIRECT AZOMETHINE DYE, COMPOSITION COMPRISING THE SAID DYE AND ITS METHOD OF PREPARATION | L'ORÉAL (FR) | 2006-08-31 | — | — | WO | disclosed |
| WO-2006089809-A1 | DYEING OF IN PARTICULAR HUMAN KERATIN MATERIALS BY DRY THERMAL TRANSFER OF A DIRECT ANTHRAQUINONE DYE, COMPOSITION COMPRISING THE SAID DYE AND ITS METHOD OF PREPARATION | L'OREAL (FR) | 2006-08-31 | — | — | WO | disclosed |
| WO-2006089806-A1 | DYEING OF IN PARTICULAR HUMAN KERATIN MATERIALS BY DRY THERMAL TRANSFER OF A DIRECT DYE, COMPOSITION COMPRISING THE SAID DYE AND ITS METHOD OF PREPARATION | L'ORÉAL (FR) | 2006-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080168608-A1 | Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Anthraquinone Dye, Composition Comprising the Said Dye and Its Method of Preparation | KRT18, DSG1, KLK5 | ALDH1A1 774/4885THRB 4056/4885TSHR 4226/4885 |
| US-20080120792-A1 | Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Azomethine Dye, Composition Comprising the Said Dye and its Method of Preparation | KRT18, IK, KLK5 | ALDH1A1 899/4885THRB 3568/4885TSHR 3805/4885 |
| US-20080148496-A1 | Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Dye, Composition Comprising the Said Dye and Its Method of Preparation | KRT18, IK, DSG1 | ALDH1A1 911/4885THRB 3514/4885TSHR 4059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.